根据计算机断层扫描数据对正常儿童和小头畸形儿童颅骨结构的形态计量学分析

Q4 Biochemistry, Genetics and Molecular Biology
-Х. Гаибов, Е.В. Захарчук, Д.П. Воробьев, S. S. Gaibov, E. V. Zakharchyk, D. P. Vorobjov
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引用次数: 0

摘要

人们越来越关注帮助因颅骨缝合线过早闭合和颅缝闭合发育而出现颅骨畸形的儿童的问题。评估颅骨畸形中的颅骨畸形通常是主观的,并且仍然是一个挑战。形态计量学研究是现代科学、实用和参考医学文献中很少涉及的一个重要部分。材料和方法。对颅骨测量数据的分析,根据计算机断层扫描结果,24名7.4±3.2个月(2-12个月)的多头畸形儿童(14名男孩,10名女孩)和25名7.2±4.8个月(2-10个月)年龄的对照组(15名男孩,9名女孩)的头部指数(CI)。CI显示正常和小头畸形颅骨线性尺寸的比值。当评估距离G-Op、CG-TS、CG-MAI、MAI-MAI、Zg-Zg、Ec-Ec、Br-Ba时,显示出最显著的差异。CG-TS、CG-MAI、MAI-MAI、Br-Ba反映颅底的变形,Zg Zg、Ec-Ec——多头畸形面部骨骼的变形。结论。基于精确的解剖标志对颅骨结构进行的全面形态计量分析表明,正常儿童和多头畸形儿童的颅骨形态存在客观差异。这些数据表明,对所有形式的头骨进行全面评估的重要性。进行这样的分析对于了解健康和疾病中头骨的所有形态变化非常重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Morphometric analysis of the structures of the skull according to computed tomography data in children in norm and in dolichocephaly
There is an increased interest in the problem of helping children with skull deformities that occur due to premature closure of cranial sutures and the development of craniosynostosis. Assessment of cranial dysmorphism in skull deformities is often subjective and remains a challenge. Morphometric studies are a significant section that is poorly covered in modern scientific, practical and reference medical literature.Material and methods. The analysis of the data of craniometric measurements, of cephalic index (CI) according to the results of computed tomography in 24 children with dolichocephaly (14 boys, 10 girls) at the age of 7.4 ± 3.2 months (2–12 months) and in the control group of 25 children (15 boys, 9 girls) at the age of 7.2 ± 4.8 months (2–12 months).Results. The data showed significant differences in children in norm and in dolichocephaly. CI shows the ratio of the linear dimensions of the skull in normal and dolichocephaly. The most significant differences were revealed when assessing the distances G-Op, CG-TS, CG-MAI, MAI-MAI, Zg-Zg, Ec-Ec, Br-Ba. CG-TS, CG-MAI, MAI-MAI, Br-Ba reflect deformation of the skull base, and Zg-Zg, Ec-Ec – deformation of the facial skeleton in dolichocephaly.Conclusions. A comprehensive morphometric analysis of the skull structures based on precise anatomical landmarks demonstrated objective differences in the morphology of the skull in children with normal conditions and with dolichocephaly. The data indicate the importance of a comprehensive assessment of changes in the skull for all forms of the skull. Carrying out such an analysis is important for understanding all morphological changes in the skull in health and disease.
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CiteScore
0.40
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