亚洲髋部骨折,特别关注老年人:简评

C. Cheung, S. Ho, S. Krishnamoorthy, Xiaowen Zhang
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引用次数: 1

摘要

骨质疏松症是一种全球性的普遍疾病,其临床结果是脆性骨折。在所有脆性骨折中,髋部骨折主要与发病率、不活动和死亡率相关。虽然20世纪90年代的早期研究预测,到2050年,世界上一半的髋部骨折将发生在亚洲,但亚洲的流行病学研究并不充分。另一方面,尽管一些国家或地区报道了髋部骨折发生率趋于稳定或下降的趋势,但由于老年人口的快速增加,髋部骨折的总数仍可能增加。老年人通常骨折发生率最高,而骨质疏松症的治疗和管理对他们来说是次优的。治疗不足可能是由于“不利的”风险-收益状况,缺乏针对老年人的骨折预测工具,以及存在多种合共病。制定老年人骨质疏松症的战略管理计划,有助于应对即将到来的“骨折海啸”,实现老年人的“健康老龄化”目标。在这里,我们回顾了最近亚洲髋部骨折的流行病学研究,重点是目前的治疗、骨折预测和最年长老年人的合并症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hip Fracture in Asia with a Special Focus in the Oldest Old: A Brief Review
Osteoporosis is a prevalent disease globally, with fragility fracture being the clinical outcome. Hip fracture is mostly associated with morbidity, immobility, and mortality among all fragility fractures. Although earlier studies in the 1990s projected that half of the hip fractures in the world will occur in Asia by 2050, epidemiology studies in Asia are inadequate. On the other hand, although the stabilizing or reducing trend of hip fracture incidence was reported in some countries or regions, the total number of hip fractures may still increase due to the rapid increase of the oldest old population. The oldest old usually have the highest fracture incidence, while the available treatment and management of osteoporosis for them are suboptimal. The undertreatment could be due to the “unfavorable” risk–benefit profile, lack of fracture prediction tool for the oldest old, and the presence of multiple comorbidities. A strategic management plan for osteoporosis in the oldest old can help cope with the coming “fracture tsunami” and achieve the “healthy aging” goal among the oldest old. Here, we reviewed the recent Asian epidemiology studies on hip fracture, focusing on the current treatment, fracture prediction, and comorbidities of the oldest old.
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