抗痛风药物分析方法综述

IF 0.7 Q4 PHARMACOLOGY & PHARMACY

Journal of Reports in Pharmaceutical Sciences Pub Date : 2020-01-01 DOI:10.4103/jrptps.JRPTPS_32_19

R. Kachave, P. Mandlik, S. Wakchaure

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引用次数: 1

摘要

本研究的目的是提供用于治疗痛风的原料药和制剂的杂质谱分析、力降解和生物分析的分析角度的发展信息。这些信息是根据发表年份、基质(活性药物成分、剂型和生物液)、样品制备技术、色谱柱和洗脱类型(等压或梯度)、检测器和用于分析的药物治疗类别进行讨论的。它主要侧重于分析方法，包括在不同的药物和生物基质中用于杂质、降解物和代谢物的鉴定和定量的连字符技术。

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A review on analytical methods of antigout agents

The aim of this study was to provide information of the development in analytical perspective of impurity profiling, force degradation, and bioanalysis of pharmaceutical drug substance and drug products used for the treatment of gout. This information was discussed on the basis of year of publication, matrix (active pharmaceutical ingredient, dosage form, and biological fluid), sample preparation technique, column and types of elution in chromatography (isocratic or gradient), detector, and therapeutic categories of drug, which were used for analysis. It focuses mainly on analytical methods including hyphenated techniques for the identification and quantification of impurity, degradants, and metabolites in different pharmaceutical and biological matrices.

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来源期刊

Journal of Reports in Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： The Journal of Reports in Pharmaceutical Sciences(JRPS) is a biannually peer-reviewed multi-disciplinary pharmaceutical publication to serve as a means for scientific information exchange in the international pharmaceutical forum. It accepts novel findings that contribute to advancement of scientific knowledge in pharmaceutical fields that not published or under consideration for publication anywhere else for publication in JRPS as original research article. all aspects of pharmaceutical sciences consist of medicinal chemistry, molecular modeling, drug design, pharmaceutics, biopharmacy, pharmaceutical nanotechnology, pharmacognosy, natural products, pharmaceutical biotechnology, pharmacology, toxicology and clinical pharmacy.