60年来超高分子量聚乙烯在重建手术中的应用

IF 16.8 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

International Materials Reviews Pub Date : 2022-05-20 DOI:10.1080/09506608.2022.2047419

Vidushi Sharma, Sheetal Chowdhury, N. Keshavan, B. Basu

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引用次数: 9

摘要

超高分子量聚乙烯(UHMWPE)材料在重建手术领域发挥了重要作用，特别是作为全髋关节置换术(THR)的髋臼衬套/套，以及全膝关节置换术(TKR)的胫骨植入物。本文综述了超高分子量聚乙烯及其衍生物的加工-结构-性能关系的关键因素。将重点讨论超高分子量聚乙烯共混/复合配方、维生素e增强或高度交联变体的临床相关特性。此外，我们还提供了磨损碎片在炎症和骨溶解中的作用的临床见解。超高分子量聚乙烯增材制造的相对未开发领域。最后，强调了UHMWPE增材制造的相对未开发领域以及与下一代UHMWPE植入物相关的机会。图形抽象

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Six decades of UHMWPE in reconstructive surgery

ABSTRACT Ultra-high molecular weight polyethylene (UHMWPE) materials have played a significant role in the field of reconstructive surgery, particularly as acetabular liners/sockets for total hip joint replacement (THR), and tibial inserts for total knee joint replacement (TKR). This review aims to provide a perspective on key elements regarding the processing–structure–property relationship of UHMWPE and derivatives. Much emphasis will be provided to discuss the clinically relevant properties of UHMWPE blend/composite formulation, Vitamin-E reinforced or highly crosslinked variants. In addition, we provide clinical insights into the role of wear debris in inflammation and osteolysis. The relatively unexplored domain of UHMWPE additive manufacturing. Finally, the relatively unexplored domain of UHMWPE additive manufacturing and the opportunities associated with the next generation of UHMWPE implants are highlighted. GRAPHICAL ABSTRACT

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来源期刊

International Materials Reviews 工程技术-材料科学：综合

CiteScore

28.50

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： International Materials Reviews (IMR) is a comprehensive publication that provides in-depth coverage of the current state and advancements in various materials technologies. With contributions from internationally respected experts, IMR offers a thorough analysis of the subject matter. It undergoes rigorous evaluation by committees in the United States and United Kingdom for ensuring the highest quality of content. Published by Sage on behalf of ASM International and the Institute of Materials, Minerals and Mining (UK), IMR is a valuable resource for professionals in the field. It is available online through Sage's platform, facilitating convenient access to its wealth of information. Jointly produced by ASM International and the Institute of Materials, Minerals and Mining (UK), IMR focuses on technologies that impact industries dealing with metals, structural ceramics, composite materials, and electronic materials. Its coverage spans from practical applications to theoretical and practical aspects of material extraction, production, fabrication, properties, and behavior.