淋巴细胞指数/C反应蛋白降低是新冠肺炎患者死亡率的预后因素

Q4 Immunology and Microbiology
Ana Paula Salaverry Enriquez
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引用次数: 0

摘要

本研究的目的是确定淋巴细胞/C反应蛋白(L/CRP)比率降低是新冠肺炎患者死亡率的预后因素。该研究对93名患者进行了分析性、观察性、回顾性和纵向队列设计。获得了定性变量的频率分布数据以及定量变量的集中度和分散度的度量。此外,使用了卡方(X2)检验,因此,如果p小于0.05,则相关性被认为是显著的。最后,在定性变量中,计算L/CRP指数相对于新冠肺炎死亡风险的相对风险。然后,对在双变量分析中显著的干预变量进行多变量分析,并进行逻辑回归。结果显示,在93名患者中,44.1%的患者死亡。除此之外,研究发现,60岁以上的年龄、淋巴细胞计数正常和L/CRP指数下降是新冠肺炎患者死亡的危险因素。总之,L/CRP比率降低是新冠肺炎患者死亡率的预后因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Índice linfocito/proteína C reactiva disminuido como factor pronóstico de mortalidad en pacientes con COVID-19
The objective of this study was to determine that the decreased lymphocyte/C-reactive protein (L/CRP) ratio is a prognostic factor for mortality in patients with COVID-19. The research had an analytical, observational, retrospective and longitudinal cohort design carried out in 93 patients. The frequency distribution data of qualitative variables and the measures of centralization and dispersion of quantitative variables were obtained. In addition, the Chi Square (X2) test was used, therefore, the associations were considered significant if p was less than 0.05. Finally, among the qualitative variables, the relative risk of the L/CRP index with respect to the risk of mortality in COVID-19 was calculated. Afterwards, the multivariate analysis was carried out with logistic regression for the intervening variables that were significant in the bivariate analysis. In the results, of the 93 patients, it was possible to show that 44.1% died. In addition to this, it was found that age over 60 years, normal lymphocyte counts and decreased values of the L/CRP Index proved to be a risk factor for mortality in patients with COVID-19. In conclusion, the decreased L/CRP ratio is a prognostic factor for mortality in patients with COVID-19.
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来源期刊
Boletin De Malariologia Y Salud Ambiental
Boletin De Malariologia Y Salud Ambiental INFECTIOUS DISEASES-PARASITOLOGY
CiteScore
0.40
自引率
0.00%
发文量
51
期刊介绍: Information not localized
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