{"title":"坏死性胰腺炎合并胰外感染的细菌谱及药物敏感性分析","authors":"Jiongdi Lu, Yi-Xuan Dıng, F. Cao, Fei Lı","doi":"10.3760/CMA.J.ISSN.1007-631X.2019.11.008","DOIUrl":null,"url":null,"abstract":"Objective \nTo survey the bacterial spectrum and drug sensitivity in patients with necrotizing pancreatitis (NP) complicating with extra-pancreatic infection(EPI). \n \n \nMethods \nThe clinical data of 79 NP with EPI patients from Jan 1, 2016 to Dec 31, 2018 were retrospectively analyzed. The strain identification and drug sensitivity test of positive specimens were statistically analyzed. \n \n \nResults \nA total of 219 strains of pathogenic bacteria were isolated, including 106(48.4%) gram-negative bacteria, 69(31.5%) gram-positive bacteria and 44(20.1%) fungi. The common pathogenic bacteria were Pseudomonas aeruginosa (10.1%), Staphylococcus epidermidis (9.1%) and Acinetobacter baumannii (9.1%). The resistance of common extrapancreatic pathogenic bacteria to penicillin and first and second generation cephalosporins was common. \n \n \nConclusions \nThe pathogenic bacteria of NP complicated with EPI were mainly Gram-negative bacteria, and the common sites of extra-pancreatic infection were bacteremia and respiratory tract. The third, fourth generation cephalosporins or carbapenems can be used empirically. \n \n \nKey words: \nPancreatitis, acute necrotizing; Infection; Pathogenic bacteria; Drug sensitivity test","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bacterial spectrum and drug sensitivity analysis in necrotizing pancreatitis with extra-pancreatic infection\",\"authors\":\"Jiongdi Lu, Yi-Xuan Dıng, F. Cao, Fei Lı\",\"doi\":\"10.3760/CMA.J.ISSN.1007-631X.2019.11.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nTo survey the bacterial spectrum and drug sensitivity in patients with necrotizing pancreatitis (NP) complicating with extra-pancreatic infection(EPI). \\n \\n \\nMethods \\nThe clinical data of 79 NP with EPI patients from Jan 1, 2016 to Dec 31, 2018 were retrospectively analyzed. The strain identification and drug sensitivity test of positive specimens were statistically analyzed. \\n \\n \\nResults \\nA total of 219 strains of pathogenic bacteria were isolated, including 106(48.4%) gram-negative bacteria, 69(31.5%) gram-positive bacteria and 44(20.1%) fungi. The common pathogenic bacteria were Pseudomonas aeruginosa (10.1%), Staphylococcus epidermidis (9.1%) and Acinetobacter baumannii (9.1%). The resistance of common extrapancreatic pathogenic bacteria to penicillin and first and second generation cephalosporins was common. \\n \\n \\nConclusions \\nThe pathogenic bacteria of NP complicated with EPI were mainly Gram-negative bacteria, and the common sites of extra-pancreatic infection were bacteremia and respiratory tract. The third, fourth generation cephalosporins or carbapenems can be used empirically. \\n \\n \\nKey words: \\nPancreatitis, acute necrotizing; Infection; Pathogenic bacteria; Drug sensitivity test\",\"PeriodicalId\":66425,\"journal\":{\"name\":\"中华普通外科杂志\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华普通外科杂志\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2019.11.008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华普通外科杂志","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2019.11.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Bacterial spectrum and drug sensitivity analysis in necrotizing pancreatitis with extra-pancreatic infection
Objective
To survey the bacterial spectrum and drug sensitivity in patients with necrotizing pancreatitis (NP) complicating with extra-pancreatic infection(EPI).
Methods
The clinical data of 79 NP with EPI patients from Jan 1, 2016 to Dec 31, 2018 were retrospectively analyzed. The strain identification and drug sensitivity test of positive specimens were statistically analyzed.
Results
A total of 219 strains of pathogenic bacteria were isolated, including 106(48.4%) gram-negative bacteria, 69(31.5%) gram-positive bacteria and 44(20.1%) fungi. The common pathogenic bacteria were Pseudomonas aeruginosa (10.1%), Staphylococcus epidermidis (9.1%) and Acinetobacter baumannii (9.1%). The resistance of common extrapancreatic pathogenic bacteria to penicillin and first and second generation cephalosporins was common.
Conclusions
The pathogenic bacteria of NP complicated with EPI were mainly Gram-negative bacteria, and the common sites of extra-pancreatic infection were bacteremia and respiratory tract. The third, fourth generation cephalosporins or carbapenems can be used empirically.
Key words:
Pancreatitis, acute necrotizing; Infection; Pathogenic bacteria; Drug sensitivity test