Metaphase前期拉伸：再审视

DNA (Mary Ann Liebert, Inc.) Pub Date : 2021-06-29 DOI:10.3390/dna1010002

Megan A. Czekalski, L. Paliulis

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引用次数: 1

摘要

中期前伸展是一个由杰出的细胞生物学家Sally Hughes-Schrader于1950年首次创造的术语，用于描述在相粒昆虫和螳螂的初级精母细胞中观察到的中期前染色体的延伸。自Hughes-Schrader最初的观察以来，许多研究小组的研究揭示了染色体在中期之前如何以及为什么会延长的原因。在这篇综述中，我们描述了Hughes-Schrader的初步发现，并讨论了最近的工作如何阐明并为这一很久以前观察到的现象提供了一些机制解释。

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The Pre-Metaphase Stretch: A Re-Examination

Pre-metaphase stretch is a term first coined by the preeminent cell biologist Sally Hughes-Schrader in 1950 to describe an elongation of prometaphase chromosomes observed in the primary spermatocytes of phasmid insects and praying mantids. Research from many groups since Hughes-Schrader’s initial observation has revealed reasons for both how and why chromosomes might elongate prior to metaphase. In this review, we describe Hughes-Schrader’s initial findings and discuss how recent work illuminates and provides some mechanistic explanation for this long-ago observed phenomenon.

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DNA (Mary Ann Liebert, Inc.)

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