{"title":"CACIPLIQ20®基质疗法作为难愈合伤口治疗剂10年实践综述:疗效、成本效益和未来前景","authors":"Denis Barritault","doi":"10.1016/j.wndm.2020.100180","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Chronic, non-healing wounds remain a major challenge for health care practitioners and for society in general, both in terms of the enormous economic burden on health care systems and the decreased quality of life of the patients.</p></div><div><h3>Objective and methods</h3><p>To provide the first overview of the use of CACIPLIQ20®, a matrix therapy agent, over the past 10 years on 4 continents and 15 countries. CACIPLIQ20® was used as a last resort for these wounds, which had not shown any evidence of improvement with conventional care and had no expectation of healing. Cases with fully healed wounds were evaluated in order to assess how long complete wound healing can be achieved using this therapy.</p></div><div><h3>Results</h3><p>Through the evaluation of a selected 119 cases, we found that regardless of wound size or age, treatment with CACIPLIQ20® resulted in complete healing (full closure) in about 2 months of a variety of chronic wounds including diabetic foot ulcers, burns, post-amputation/surgical wounds, among others. Moreover, CACIPLIQ20® was found to be cost-effective, it’s current spray format potentially costing 74 euros (64 GBP) to treat wounds measuring an average area of 14 cm<sup>2</sup> to wound closure. CACIPLIQ20® was also widely reported to provide marked pain relief as a consequence of healing.</p></div><div><h3>Conclusions</h3><p>CACIPLIQ20® can heal chronic wounds of various etiologies, sizes and ages in approximately two months, while being cost-effective. By doing so, this treatment can provide major improvement of quality of life through rapid and complete healing of chronic, hard-to-heal wounds and can reduce the economic burden of chronic wounds for health care agencies.</p></div>","PeriodicalId":38278,"journal":{"name":"Wound Medicine","volume":"28 ","pages":"Article 100180"},"PeriodicalIF":0.0000,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wndm.2020.100180","citationCount":"3","resultStr":"{\"title\":\"Overview of 10 years of practice with CACIPLIQ20® matrix therapy as a healing agent for hard to heal wounds: Efficacy, cost-effectiveness and future perspectives\",\"authors\":\"Denis Barritault\",\"doi\":\"10.1016/j.wndm.2020.100180\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Chronic, non-healing wounds remain a major challenge for health care practitioners and for society in general, both in terms of the enormous economic burden on health care systems and the decreased quality of life of the patients.</p></div><div><h3>Objective and methods</h3><p>To provide the first overview of the use of CACIPLIQ20®, a matrix therapy agent, over the past 10 years on 4 continents and 15 countries. CACIPLIQ20® was used as a last resort for these wounds, which had not shown any evidence of improvement with conventional care and had no expectation of healing. Cases with fully healed wounds were evaluated in order to assess how long complete wound healing can be achieved using this therapy.</p></div><div><h3>Results</h3><p>Through the evaluation of a selected 119 cases, we found that regardless of wound size or age, treatment with CACIPLIQ20® resulted in complete healing (full closure) in about 2 months of a variety of chronic wounds including diabetic foot ulcers, burns, post-amputation/surgical wounds, among others. Moreover, CACIPLIQ20® was found to be cost-effective, it’s current spray format potentially costing 74 euros (64 GBP) to treat wounds measuring an average area of 14 cm<sup>2</sup> to wound closure. CACIPLIQ20® was also widely reported to provide marked pain relief as a consequence of healing.</p></div><div><h3>Conclusions</h3><p>CACIPLIQ20® can heal chronic wounds of various etiologies, sizes and ages in approximately two months, while being cost-effective. By doing so, this treatment can provide major improvement of quality of life through rapid and complete healing of chronic, hard-to-heal wounds and can reduce the economic burden of chronic wounds for health care agencies.</p></div>\",\"PeriodicalId\":38278,\"journal\":{\"name\":\"Wound Medicine\",\"volume\":\"28 \",\"pages\":\"Article 100180\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.wndm.2020.100180\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Wound Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213909520300045\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wound Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213909520300045","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Overview of 10 years of practice with CACIPLIQ20® matrix therapy as a healing agent for hard to heal wounds: Efficacy, cost-effectiveness and future perspectives
Background
Chronic, non-healing wounds remain a major challenge for health care practitioners and for society in general, both in terms of the enormous economic burden on health care systems and the decreased quality of life of the patients.
Objective and methods
To provide the first overview of the use of CACIPLIQ20®, a matrix therapy agent, over the past 10 years on 4 continents and 15 countries. CACIPLIQ20® was used as a last resort for these wounds, which had not shown any evidence of improvement with conventional care and had no expectation of healing. Cases with fully healed wounds were evaluated in order to assess how long complete wound healing can be achieved using this therapy.
Results
Through the evaluation of a selected 119 cases, we found that regardless of wound size or age, treatment with CACIPLIQ20® resulted in complete healing (full closure) in about 2 months of a variety of chronic wounds including diabetic foot ulcers, burns, post-amputation/surgical wounds, among others. Moreover, CACIPLIQ20® was found to be cost-effective, it’s current spray format potentially costing 74 euros (64 GBP) to treat wounds measuring an average area of 14 cm2 to wound closure. CACIPLIQ20® was also widely reported to provide marked pain relief as a consequence of healing.
Conclusions
CACIPLIQ20® can heal chronic wounds of various etiologies, sizes and ages in approximately two months, while being cost-effective. By doing so, this treatment can provide major improvement of quality of life through rapid and complete healing of chronic, hard-to-heal wounds and can reduce the economic burden of chronic wounds for health care agencies.