{"title":"阳极氧化和退火钛表面上小鼠前成骨细胞的ALP水平","authors":"S. Yeniyol, J. Ricci","doi":"10.17096/JIUFD.78387","DOIUrl":null,"url":null,"abstract":"Purpose: The aim of this study was to evaluate the initial adhesion morphology and alkaline phosphatase activity (ALP) of murine pre-osteoblastic MC3T3-E1 cells on anatase/rutile mixed-phase TiO 2 thin films with photocatalytical activity that previously confirmed antibacterial properties. Materials and Methods: Anatase/rutile mixed-phaseTiO 2 thin films fabricated by anodization and annealing of cpTi were cultured by MC3T3-E1 to evaluate the initial cellular adhesion morphology and ALP activity in vitro. Results: Compared with cpTi substrates and the control group, MC3T3-E1 cells cultured on anodized and annealed titanium substrates exhibited similar ALP levels after cell culture day 9. Conclusion: Anodizing and annealing processes fabricate multifunctional surfaces on cpTi with improved osteogenic properties for implants.","PeriodicalId":30947,"journal":{"name":"Journal of Istanbul University Faculty of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2017-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ALP LEVELS OF MURINE PRE-OSTEOBLASTIC CELLS ON ANODIZED AND ANNEALED TITANIUM SURFACES\",\"authors\":\"S. Yeniyol, J. Ricci\",\"doi\":\"10.17096/JIUFD.78387\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: The aim of this study was to evaluate the initial adhesion morphology and alkaline phosphatase activity (ALP) of murine pre-osteoblastic MC3T3-E1 cells on anatase/rutile mixed-phase TiO 2 thin films with photocatalytical activity that previously confirmed antibacterial properties. Materials and Methods: Anatase/rutile mixed-phaseTiO 2 thin films fabricated by anodization and annealing of cpTi were cultured by MC3T3-E1 to evaluate the initial cellular adhesion morphology and ALP activity in vitro. Results: Compared with cpTi substrates and the control group, MC3T3-E1 cells cultured on anodized and annealed titanium substrates exhibited similar ALP levels after cell culture day 9. Conclusion: Anodizing and annealing processes fabricate multifunctional surfaces on cpTi with improved osteogenic properties for implants.\",\"PeriodicalId\":30947,\"journal\":{\"name\":\"Journal of Istanbul University Faculty of Dentistry\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Istanbul University Faculty of Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17096/JIUFD.78387\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Istanbul University Faculty of Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17096/JIUFD.78387","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ALP LEVELS OF MURINE PRE-OSTEOBLASTIC CELLS ON ANODIZED AND ANNEALED TITANIUM SURFACES
Purpose: The aim of this study was to evaluate the initial adhesion morphology and alkaline phosphatase activity (ALP) of murine pre-osteoblastic MC3T3-E1 cells on anatase/rutile mixed-phase TiO 2 thin films with photocatalytical activity that previously confirmed antibacterial properties. Materials and Methods: Anatase/rutile mixed-phaseTiO 2 thin films fabricated by anodization and annealing of cpTi were cultured by MC3T3-E1 to evaluate the initial cellular adhesion morphology and ALP activity in vitro. Results: Compared with cpTi substrates and the control group, MC3T3-E1 cells cultured on anodized and annealed titanium substrates exhibited similar ALP levels after cell culture day 9. Conclusion: Anodizing and annealing processes fabricate multifunctional surfaces on cpTi with improved osteogenic properties for implants.
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