溶栓治疗预测急性缺血性脑卒中患者的动态康复

IF 0.6 Q4 CLINICAL NEUROLOGY

Future Neurology Pub Date : 2020-05-01 DOI:10.2217/fnl-2020-0002

M. Scalise, L. Brechtel, Zach Conn, B. Bailes, Jordan C. Gainey, T. Nathaniel

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引用次数: 9

摘要

目的：本研究的目的是确定溶栓治疗后临床表现对功能性步行的预测价值。材料与方法：采用Logistic回归分析确定功能性步行与溶栓治疗之间的关系。结果与结论：在结果中，西班牙裔（OR）：2.808；p=0.034；95%可信区间：1.08–7.30），美国国家卫生研究所高卒中量表（NIHSS）（OR:1.112；p≤0.001；95%可信区间1.06–1.17），虚弱/轻瘫（OR:1.796；p=0.005；95%可信范围1.19–2.71），Broca失语症（OR:1.571；p=0.003；95%CI=1.16-2.12）和抗高血压药物（OR:11.530；p=0.034；95%CI:1.03-2.26）与未接受溶栓治疗的患者的活动能力改善有关。在接受溶栓治疗的患者中，Broca失语症与功能结果的改善有关。

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Predicting ambulatory recovery in acute ischemic stroke patients with thrombolytic therapy

Aim: The aim of this study was to determine the predictive value of clinical presentations on functional ambulation following thrombolytic therapy. Materials & methods: Logistic regression analysis was used to determine associations between functional ambulation and thrombolytic therapy. Results & conclusion: In the results, Hispanic ethnicity (odds ratio (OR): 2.808; p = 0.034; 95% CI: 1.08–7.30), high National Institute of Health Stroke Scale (NIHSS) (OR: 1.112; p ≤ 0.001; 95% CI: 1.06–1.17), weakness/paresis (OR: 1.796; p = 0.005; 95% CI: 1.19–2.71), Broca’s aphasia (OR: 1.571; p = 0.003; 95% CI = 1.16–2.12) and antihypertensive medication (OR: 1.530; p = 0.034; 95% CI: 1.03–2.26) were associated with an improved ambulation in patients without thrombolytic therapy. In thrombolytic treated patients, Broca’s aphasia was associated with improved functional outcome.

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来源期刊

Future Neurology CLINICAL NEUROLOGY-

CiteScore

2.10

自引率

0.00%

发文量

期刊介绍： The neurological landscape is changing rapidly. From the technological perspective, advanced molecular approaches and imaging modalities have greatly increased our understanding of neurological disease, with enhanced prospects for effective treatments in common but very serious disorders such as stroke, epilepsy, multiple sclerosis and Parkinson’s disease. Nevertheless, at the same time, the healthcare community is increasingly challenged by the rise in neurodegenerative diseases consequent upon demographic changes in developed countries.