转移性前列腺癌雄激素剥夺治疗的选择是什么:外科还是医学?

IF 1 Q4 UROLOGY & NEPHROLOGY
Huseyin Salih Semiz, Erdem Kısa, Eda Caliskan Yildirim, E. Atağ, Mehmet Emin Arayici, T. Muezzinoğlu, A. Karaoglu
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引用次数: 1

摘要

目的:在诊断时,大约16.5%的癌症患者是转移性的。转移性前列腺癌症治疗的主要框架是雄激素剥夺疗法,该疗法通过手术或药物进行。本研究的目的是评估肿瘤学家和泌尿科医生对睾丸切除术作为雄激素剥夺疗法的态度。材料和方法:在泌尿外科工作的387名医生(n = 217)和医学肿瘤学(n = 170)纳入本描述性研究。数据是通过电子调查收集的。结果:只有7.5%的参与者表示他们为患者提供了手术阉割。在转移性去势敏感前列腺癌的治疗中,泌尿科医生比肿瘤学家更喜欢手术去势(P = .003)。医学肿瘤学家较少选择手术阉割的原因是,这是一种侵入性手术,有发病率和死亡率的风险,住院费用高,并可能导致患者身体形象恶化(P<.05)。结论:本研究表明,医生不太可能将睾丸切除术作为雄激素剥夺疗法。尽管最重要的原因是患者的偏好,但对患者的治疗选择有偏见,医生对睾丸切除术缺乏了解,以及制药行业的影响也应牢记在心。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
What Is Your Choice for Androgen Deprivation Therapy in Metastatic Prostate Carcinoma: Surgical or Medical?
Objective : At the time of diagnosis, approximately 16.5% of prostate cancer patients are metastatic. The main framework of metastatic prostate cancer treatment is androgen deprivation therapy, which is performed surgically or medically. The aim of this study is to evaluate the attitudes of medical oncologists and urologists about orchiectomy as androgen deprivation therapy. Material and Methods: A total of 387 physicians working in the Departments of Urology (n = 217) and Medical Oncology (n = 170) were included in this descriptive study. Data were collected through an electronic survey. Results: Only 7.5% of participants indicated that they offered surgical castration to their patients. Urologists preferred surgical castration more than oncologists for the treatment of metastatic castration-sensitive prostate carcinoma (P = .003). The reasons why medical oncologists preferred surgical castration less are that it is an invasive procedure, has risk of morbidity and mortality, high cost of hospitalization, and may cause deterioration of the patient's body image (P < .05). Conclusion: This study showed that physicians were less likely to perform orchiectomy as an androgen deprivation therapy. Although the most important reason for this is the patient preference, the biased presentation of treatment options to patients, the lack of knowledge of physicians about orchiectomy, and the effect of the pharmaceutical industry should also be kept in mind.
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来源期刊
Turkish journal of urology
Turkish journal of urology Medicine-Urology
CiteScore
2.10
自引率
0.00%
发文量
53
期刊介绍: The aim of the Turkish Journal of Urology is to contribute to the literature by publishing scientifically high-quality research articles as well as reviews, editorials, letters to the editor and case reports. The journal’s target audience includes, urology specialists, medical specialty fellows and other specialists and practitioners who are interested in the field of urology.
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