J. Lukose, G. Mohan, N. Mithun, S. Shastry, C. Santhosh
{"title":"光学陷阱结合拉曼光谱探测某些静脉输液中的红细胞行为","authors":"J. Lukose, G. Mohan, N. Mithun, S. Shastry, C. Santhosh","doi":"10.18287/jbpe19.05.040302","DOIUrl":null,"url":null,"abstract":". Systematic studies on a live, individual human red blood cell without any chemical fixation can be realized with the aid of optical tweezers. In the present work, the behavior of human red blood cell in dextrose containing intravenous fluids and blood plasma were investigated and compared using a home-made near-IR Laser Tweezers Raman spectrometer. Significant spectral variations in Raman signatures exist between the RBCs in plasma and dextrose containing intravenous fluids, which mainly comprise of the hemoglobin oxygenation-deoxygenation transition as well as the heme aggregation markers . © 2019 Journal of Biomedical Photonics & Engineering.","PeriodicalId":52398,"journal":{"name":"Journal of Biomedical Photonics and Engineering","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Optical Trap Combined with Raman Spectroscopy to Probe Red Blood Cell Behaviour in Certain Intravenous Fluids\",\"authors\":\"J. Lukose, G. Mohan, N. Mithun, S. Shastry, C. Santhosh\",\"doi\":\"10.18287/jbpe19.05.040302\",\"DOIUrl\":null,\"url\":null,\"abstract\":\". Systematic studies on a live, individual human red blood cell without any chemical fixation can be realized with the aid of optical tweezers. In the present work, the behavior of human red blood cell in dextrose containing intravenous fluids and blood plasma were investigated and compared using a home-made near-IR Laser Tweezers Raman spectrometer. Significant spectral variations in Raman signatures exist between the RBCs in plasma and dextrose containing intravenous fluids, which mainly comprise of the hemoglobin oxygenation-deoxygenation transition as well as the heme aggregation markers . © 2019 Journal of Biomedical Photonics & Engineering.\",\"PeriodicalId\":52398,\"journal\":{\"name\":\"Journal of Biomedical Photonics and Engineering\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Biomedical Photonics and Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18287/jbpe19.05.040302\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Physics and Astronomy\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomedical Photonics and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18287/jbpe19.05.040302","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Physics and Astronomy","Score":null,"Total":0}
引用次数: 2