光学陷阱结合拉曼光谱探测某些静脉输液中的红细胞行为

Q3 Physics and Astronomy
J. Lukose, G. Mohan, N. Mithun, S. Shastry, C. Santhosh
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引用次数: 2

摘要

. 在光学镊子的帮助下,可以实现对一个活的、个体的人类红细胞的系统研究,而不需要任何化学固定。本文利用自制的近红外激光镊子拉曼光谱仪,研究了人红细胞在含葡萄糖的静脉输液和血浆中的行为,并进行了比较。血浆中的红细胞和含葡萄糖的静脉输液中的红细胞在拉曼特征上存在显著的光谱差异,主要包括血红蛋白氧-脱氧转变以及血红素聚集标记。©2019生物医学光子学与工程杂志。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optical Trap Combined with Raman Spectroscopy to Probe Red Blood Cell Behaviour in Certain Intravenous Fluids
. Systematic studies on a live, individual human red blood cell without any chemical fixation can be realized with the aid of optical tweezers. In the present work, the behavior of human red blood cell in dextrose containing intravenous fluids and blood plasma were investigated and compared using a home-made near-IR Laser Tweezers Raman spectrometer. Significant spectral variations in Raman signatures exist between the RBCs in plasma and dextrose containing intravenous fluids, which mainly comprise of the hemoglobin oxygenation-deoxygenation transition as well as the heme aggregation markers . © 2019 Journal of Biomedical Photonics & Engineering.
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来源期刊
Journal of Biomedical Photonics and Engineering
Journal of Biomedical Photonics and Engineering Physics and Astronomy-Acoustics and Ultrasonics
CiteScore
1.60
自引率
0.00%
发文量
17
审稿时长
8 weeks
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