{"title":"使用CRISPR-Cas9高通量策略同时分析多种基因组变异","authors":"P. Cordelier","doi":"10.21037/BIOTARGET.2018.10.02","DOIUrl":null,"url":null,"abstract":"In the paper untitled “high-throughput creation and functional profiling of DNA sequence variant libraries using CRISP-Cas9 in yeast” (1) published online in May 2018 in Nature Biotechnology, George M. Church, an eminent expert in CRISPR-Cas9 biology and technology, makes, yet another, giant step in the field of genomics.","PeriodicalId":92338,"journal":{"name":"Biotarget","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Simultaneous profiling of multiple genomic variations using a CRISPR-Cas9 high-throughput strategy\",\"authors\":\"P. Cordelier\",\"doi\":\"10.21037/BIOTARGET.2018.10.02\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the paper untitled “high-throughput creation and functional profiling of DNA sequence variant libraries using CRISP-Cas9 in yeast” (1) published online in May 2018 in Nature Biotechnology, George M. Church, an eminent expert in CRISPR-Cas9 biology and technology, makes, yet another, giant step in the field of genomics.\",\"PeriodicalId\":92338,\"journal\":{\"name\":\"Biotarget\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-09-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biotarget\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21037/BIOTARGET.2018.10.02\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biotarget","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21037/BIOTARGET.2018.10.02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
2018年5月，著名的CRISPR-Cas9生物学和技术专家George M. Church在《自然-生物技术》(Nature Biotechnology)上发表了一篇题为《酵母中使用CRISPR-Cas9的DNA序列变异文库的高通量创建和功能分析》(1)的论文，在基因组学领域又迈出了一大步。
Simultaneous profiling of multiple genomic variations using a CRISPR-Cas9 high-throughput strategy
In the paper untitled “high-throughput creation and functional profiling of DNA sequence variant libraries using CRISP-Cas9 in yeast” (1) published online in May 2018 in Nature Biotechnology, George M. Church, an eminent expert in CRISPR-Cas9 biology and technology, makes, yet another, giant step in the field of genomics.
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