{"title":"癌症:与表观遗传学致癌作用一致的证据","authors":"P. Riley","doi":"10.30683/1929-2279.2022.11.06","DOIUrl":null,"url":null,"abstract":"This brief review outlines the accumulated evidence which favours a mechanism of cancer generation that is dependent on defective vertical transmission of the pattern of epigenetic control of genetic expression. This model is based on the initiating lesion involving the process that copies the epigenetic features when stem cells undergo mitosis.","PeriodicalId":89799,"journal":{"name":"Journal of cancer research updates","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Cancer: Evidence Consistent with Epigenetic Carcinogenesis\",\"authors\":\"P. Riley\",\"doi\":\"10.30683/1929-2279.2022.11.06\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This brief review outlines the accumulated evidence which favours a mechanism of cancer generation that is dependent on defective vertical transmission of the pattern of epigenetic control of genetic expression. This model is based on the initiating lesion involving the process that copies the epigenetic features when stem cells undergo mitosis.\",\"PeriodicalId\":89799,\"journal\":{\"name\":\"Journal of cancer research updates\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of cancer research updates\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30683/1929-2279.2022.11.06\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cancer research updates","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30683/1929-2279.2022.11.06","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cancer: Evidence Consistent with Epigenetic Carcinogenesis
This brief review outlines the accumulated evidence which favours a mechanism of cancer generation that is dependent on defective vertical transmission of the pattern of epigenetic control of genetic expression. This model is based on the initiating lesion involving the process that copies the epigenetic features when stem cells undergo mitosis.