rac-4-碘-5-甲氧基[2.2]甲酰脲的晶体结构;一种罕见的具有平面手性的卤代甲环乙烷实例

IF 0.1 Q4 CRYSTALLOGRAPHY
Marco Blangetti, D. O’Shea
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引用次数: 0

摘要

采用5-甲氧基[2.2]元环烷(1)的低温定向邻芳基金属化反应,与碘原位反应,合成了平面手性4-碘-5-甲氧基[2.2]元环烷(2)的外消旋混合物。在100 K下用单晶x射线衍射法测定了晶体结构。该化合物在正交晶系中结晶,表征为:Pca 21, a = 13.5690(2), b = 14.2212(2), c = 7.5004(1)Å, Z = 4, V = 1447.33(4)Å 3。晶体结构采用直接法求解,并用全矩阵最小二乘法进行细化
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Crystal Structure of rac-4-Iodo-5-methoxy[2.2]metacylophane; A Rare Example of a Halogenated Metacyclophane with Planar Chirality
A racemic mixture of planar chiral 4-iodo-5-methoxy[2.2]metacylophane ( 2 ) was synthesized by the low-temperature directed ortho aryl metalation of 5-methoxy[2.2]metacyclophane ( 1 ) and subsequent in situ reaction with iodine. The crystal structure was determined by the single-crystal X-ray diffraction method at 100 K. The compound crystallized in an orthorhombic system and was characterized as: Pca 2 1 , a = 13.5690(2), b = 14.2212(2), c = 7.5004(1)Å, Z = 4, V = 1447.33(4)Å 3 . The crystal structure was solved by direct methods and refined by full-matrix least-squares
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来源期刊
CiteScore
0.60
自引率
50.00%
发文量
17
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