治疗一例近期新冠肺炎感染的难治性抗黑色素瘤分化相关基因5抗体相关皮肌炎

Cheryl Chun Man Ng, A. Leung
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引用次数: 0

摘要

已知抗黑色素瘤分化相关基因5(MDA5)抗体阳性皮肌炎与快速进展的间质性肺病和皮肤溃疡有关。即使进行强化治疗,预后也往往很差,当地队列的数据显示死亡率为37.9%[1]。在此,我们报告了一例难治性抗MDA5抗体相关皮肌炎病例,该病例发生在新冠肺炎感染后不久,并使用针对疾病病理学不同方面的联合治疗进行治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Managing a Case of Refractory Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Associated Dermatomyositis with Recent COVID-19 Infection
Anti-melanoma differentiation-associated gene 5 (MDA5) antibody positive dermatomyositis is known to associate with rapidly progressive interstitial lung disease and cutaneous ulcer. The prognosis is often poor even with intensive treatment, with data from the local cohort showing 37.9% mortality [1]. Here, we report a case of refractory anti-MDA5 antibody-associated dermatomyositis that occurs shortly after COVID-19 infection and was managed using a combination of treatments that target different aspects of disease pathology.
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