SARS-CoV-2水媒传播流行风险分析

Abdullah R. Alanzi, M. A. Parvez, Abdulrahman R. Alruwaili, M. Parvez
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引用次数: 0

摘要

我们对31项已发表的研究进行了统计分析,这些研究包括从17个国家收集的113份严重急性呼吸系统综合征冠状病毒2型阳性水样。测试样本中病毒RNA的合并估计患病率为64.1%[95%CI:51.6%,74.9%],具有相当大的异质性(I2:90.1%,P<0.001)。值得注意的是,废水、污水、医院化粪池、生物污泥和污水的RNA阳性率具有统计学意义(P<0.05)。德国、印度、土耳其、西班牙、荷兰、意大利、美国和日本的国家汇总估计患病率分别为88%(76%,94%)、85%(33%,98%)、83%(43%,97%)、78%(54%,92%)、60%(41%,77%)、53%(36%,70%)、53%、27%和25%(13%,43%)。进一步的亚组分析表明,与高收入群体相比,中等收入国家的受试水样中严重急性呼吸系统综合征冠状病毒2型的流行率明显更高。因此,我们的数据表明,基于废水的流行病学监测是社区范围内监测严重急性呼吸系统综合征冠状病毒2型的重要工具。Doi:10.28991/SciMedJ-2022-04-03-02全文:PDF
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Prevalence Risk Analysis of Waterborne Transmission of SARS-CoV-2
We statistically analyzed 31 published studies comprising 113 water samples collected from 17 countries for SARS-CoV-2 positivity. The pooled estimated prevalence of viral RNA in the tested samples was 64.1% [95% CI:51.6%, 74.9%] with considerable heterogeneity (I2: 90.1%, P<0.001). Notably, wastewater, sewage, hospital septic-tank, biological sludge, and effluent demonstrated statistical significance (P<0.05) for RNA positivity. The country-wise pooled estimated prevalence for Germany, India, Turkey, Spain, the Netherlands, Italy, the USA, and Japan were 88% (76%, 94%), 85% (33%, 98%), 83% (43%, 97%), 78% (54%, 92%), 60% (41%, 77%), 53% (36%, 70%), 53% (27%, 77%), and 25% (13%,43%), respectively. Further subgroup analyses showed that the prevalence of SARS-CoV-2 among the tested water samples was significantly higher in middle-income countries compared to high-income groups. Our data, therefore, suggests wastewater-based epidemiological surveillance as an important tool for community-wide monitoring of SARS-CoV-2. Doi: 10.28991/SciMedJ-2022-04-03-02 Full Text: PDF
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