{"title":"1例报告:女性重度β -地中海贫血不孕症的治疗","authors":"","doi":"10.26715/jbms.33_2021_2_6","DOIUrl":null,"url":null,"abstract":"Beta-thalassemia is caused by a genetically mediated deletion of beta-globin chain of hemoglobin. It is an autosomal recessive disease, which causes a severe medical condition that requires longterm blood transfusions. An impaired hypothalamic-pituitary-ovarian axis mainly causes infertility in such patients. This case report presents a 26-year-old female, a known case of beta-thalassemia major, that received monthly blood transfusions before conceiving. The patient sought consultation for the treatment of primary infertility at Bahrain Defence Force Royal Medical Services (BDF-RMS) Hospital. The patient underwent two trials of intrauterine insemination (IUI). The goal was to build up endometrial thickness by gonadotrophins administration for embryo implantation. To conclude, IUI combined with gonadotrophins for ovarian stimulation has shown success.\n\nKeywords: Artificial Insemination, Beta-Thalassemia, Hypogonadism, Infertility, Pregnancy","PeriodicalId":85027,"journal":{"name":"Journal of the Bahrain Medical Society = Majallat Jam'iyat al-Atibba' al-Bahrayniyah","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A Case Report: Infertility Treatment of a Female with Beta-thalassemia Major\",\"authors\":\"\",\"doi\":\"10.26715/jbms.33_2021_2_6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Beta-thalassemia is caused by a genetically mediated deletion of beta-globin chain of hemoglobin. It is an autosomal recessive disease, which causes a severe medical condition that requires longterm blood transfusions. An impaired hypothalamic-pituitary-ovarian axis mainly causes infertility in such patients. This case report presents a 26-year-old female, a known case of beta-thalassemia major, that received monthly blood transfusions before conceiving. The patient sought consultation for the treatment of primary infertility at Bahrain Defence Force Royal Medical Services (BDF-RMS) Hospital. The patient underwent two trials of intrauterine insemination (IUI). The goal was to build up endometrial thickness by gonadotrophins administration for embryo implantation. To conclude, IUI combined with gonadotrophins for ovarian stimulation has shown success.\\n\\nKeywords: Artificial Insemination, Beta-Thalassemia, Hypogonadism, Infertility, Pregnancy\",\"PeriodicalId\":85027,\"journal\":{\"name\":\"Journal of the Bahrain Medical Society = Majallat Jam'iyat al-Atibba' al-Bahrayniyah\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Bahrain Medical Society = Majallat Jam'iyat al-Atibba' al-Bahrayniyah\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26715/jbms.33_2021_2_6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Bahrain Medical Society = Majallat Jam'iyat al-Atibba' al-Bahrayniyah","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26715/jbms.33_2021_2_6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Case Report: Infertility Treatment of a Female with Beta-thalassemia Major
Beta-thalassemia is caused by a genetically mediated deletion of beta-globin chain of hemoglobin. It is an autosomal recessive disease, which causes a severe medical condition that requires longterm blood transfusions. An impaired hypothalamic-pituitary-ovarian axis mainly causes infertility in such patients. This case report presents a 26-year-old female, a known case of beta-thalassemia major, that received monthly blood transfusions before conceiving. The patient sought consultation for the treatment of primary infertility at Bahrain Defence Force Royal Medical Services (BDF-RMS) Hospital. The patient underwent two trials of intrauterine insemination (IUI). The goal was to build up endometrial thickness by gonadotrophins administration for embryo implantation. To conclude, IUI combined with gonadotrophins for ovarian stimulation has shown success.
Keywords: Artificial Insemination, Beta-Thalassemia, Hypogonadism, Infertility, Pregnancy
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
