De novo Reciprocal Translocation t (2;10) (q33; q11.2) With Fetal Hydrothorax: A Case Report

chromosomes 2 and 10 as t (2; 10) (q33; q11.2) de novo. Conclusion: Chromosomal abnormalities are one of the important causes of hydrothorax in the fetal period. Aneuploidy and in particular 45, X are the most common causes in the development of fetal hydrothorax. Translocation t (2;10) (q33; q11.2) is a rare chromosomal disorder and was arisen de novo in the fetus. Both parents had normal karyotypes. It is possible that mutations of genes in the translocation breakpoint loci or other chromosomes could have contributed to this anomaly in the fetus. Therefore, in the case of fetal hydrothorax, both numerical and structural chromosome abnormalities should be investigated.