{"title":"印度缺血性心脏病患者经缺血性逆转方案治疗后血压变化与V02max的相关性","authors":"R. Sane, G. Amin, Snehal Dongre, R. Mandole","doi":"10.4103/rcm.rcm_11_19","DOIUrl":null,"url":null,"abstract":"Background: The control of blood pressure (BP) is crucial in improving the outcomes of ischemic heart disease (IHD) patients. Ischemia Reversal Program (IRP) has been proved to improve the aerobic capacity of IHD patients, but further validation is needed. Methodology: This retrospective study used the data of 78 patients who had visited Madhavbaug Clinics between July and December 2018. The mean VO2max, systolic BP (SBP), and diastolic BP (DBP) with heart rate (HR) after day 30 of IRP completion was compared with that on day 1 of IRP initiation. These values were evaluated separately after classifying the patients as those being normotensive and those having either elevated BP or hypertension (HTN). Pearson's test was used to correlate the change in SBP or DBP with VO2max. Results: Majority of the patients were male (n = 54) with the mean age of 59.94 ± 9.46 years. Majority of the IHD patients had elevated BP or HTN (n = 56). The mean HR decrease in both, the normotensive group and the group with elevated BP/hypertensive patients, was found to be statistically significant at the follow-up (P < 0.05). The mean SBP (119.48 ± 12.26 mmHg vs. 135.29 ± 15.59 mmHg) and the mean DBP (77.41 ± 9.06 mmHg vs. 91.18 ± 8.86 mmHg) were significantly decreased in the hypertensive group of patients at the follow-up (P < 0.05). For the normotensive patients, they were maintained in the normal range (P > 0.05). The negative correlations of SBP (R = −0.12, P > 0.05) and DBP (R = −0.32, P < 0.05) changes with VO2maxchange were found. Conclusion: IRP increased the VO2maxand reduced the BP in IHD patients with elevated BP. The reduction in BP correlated with an increase in VO2maxin IHD patients.","PeriodicalId":21031,"journal":{"name":"Research in Cardiovascular Medicine","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Correlation between Change in Blood Pressure and V02max in Indian Patients of Ischemic Heart Disease after Ischemic Reversal Program Therapy\",\"authors\":\"R. Sane, G. Amin, Snehal Dongre, R. Mandole\",\"doi\":\"10.4103/rcm.rcm_11_19\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The control of blood pressure (BP) is crucial in improving the outcomes of ischemic heart disease (IHD) patients. Ischemia Reversal Program (IRP) has been proved to improve the aerobic capacity of IHD patients, but further validation is needed. Methodology: This retrospective study used the data of 78 patients who had visited Madhavbaug Clinics between July and December 2018. The mean VO2max, systolic BP (SBP), and diastolic BP (DBP) with heart rate (HR) after day 30 of IRP completion was compared with that on day 1 of IRP initiation. These values were evaluated separately after classifying the patients as those being normotensive and those having either elevated BP or hypertension (HTN). Pearson's test was used to correlate the change in SBP or DBP with VO2max. Results: Majority of the patients were male (n = 54) with the mean age of 59.94 ± 9.46 years. Majority of the IHD patients had elevated BP or HTN (n = 56). The mean HR decrease in both, the normotensive group and the group with elevated BP/hypertensive patients, was found to be statistically significant at the follow-up (P < 0.05). The mean SBP (119.48 ± 12.26 mmHg vs. 135.29 ± 15.59 mmHg) and the mean DBP (77.41 ± 9.06 mmHg vs. 91.18 ± 8.86 mmHg) were significantly decreased in the hypertensive group of patients at the follow-up (P < 0.05). For the normotensive patients, they were maintained in the normal range (P > 0.05). The negative correlations of SBP (R = −0.12, P > 0.05) and DBP (R = −0.32, P < 0.05) changes with VO2maxchange were found. Conclusion: IRP increased the VO2maxand reduced the BP in IHD patients with elevated BP. The reduction in BP correlated with an increase in VO2maxin IHD patients.\",\"PeriodicalId\":21031,\"journal\":{\"name\":\"Research in Cardiovascular Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2019-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research in Cardiovascular Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/rcm.rcm_11_19\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research in Cardiovascular Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/rcm.rcm_11_19","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
背景:控制血压对改善缺血性心脏病(IHD)患者的预后至关重要。缺血逆转程序(IRP)已被证明可以提高IHD患者的有氧能力,但还需要进一步验证。方法:这项回顾性研究使用了2018年7月至12月期间访问Madhavbaug诊所的78名患者的数据。将IRP完成后第30天的平均VO2max、收缩压(SBP)和舒张压(DBP)与心率(HR)与IRP开始后第1天的平均值进行比较。在将患者分为血压正常的患者和血压升高或高血压(HTN)的患者后,分别评估这些值。Pearson检验用于将SBP或DBP的变化与VO2max相关联。结果:患者多为男性(n=54),平均年龄59.94±9.46岁。大多数IHD患者的血压或HTN升高(n=56)。血压正常组和血压升高/高血压患者组的平均HR均降低,在随访时发现具有统计学意义(P<0.05)。高血压组患者的平均收缩压(119.48±12.26 mmHg vs.135.29±15.59 mmHg)和平均舒张压(77.41±9.06 mmHg vs 91.18±8.86 mmHg)在随访时显著降低(P<0.05),SBP(R=-0.12,P>0.05)和DBP(R=-0.32,P<0.05)变化与VO2max变化呈负相关。结论:IRP可提高血压升高的IHD患者的最大摄氧量,降低血压。IHD患者血压降低与VO2maxin增加相关。
Correlation between Change in Blood Pressure and V02max in Indian Patients of Ischemic Heart Disease after Ischemic Reversal Program Therapy
Background: The control of blood pressure (BP) is crucial in improving the outcomes of ischemic heart disease (IHD) patients. Ischemia Reversal Program (IRP) has been proved to improve the aerobic capacity of IHD patients, but further validation is needed. Methodology: This retrospective study used the data of 78 patients who had visited Madhavbaug Clinics between July and December 2018. The mean VO2max, systolic BP (SBP), and diastolic BP (DBP) with heart rate (HR) after day 30 of IRP completion was compared with that on day 1 of IRP initiation. These values were evaluated separately after classifying the patients as those being normotensive and those having either elevated BP or hypertension (HTN). Pearson's test was used to correlate the change in SBP or DBP with VO2max. Results: Majority of the patients were male (n = 54) with the mean age of 59.94 ± 9.46 years. Majority of the IHD patients had elevated BP or HTN (n = 56). The mean HR decrease in both, the normotensive group and the group with elevated BP/hypertensive patients, was found to be statistically significant at the follow-up (P < 0.05). The mean SBP (119.48 ± 12.26 mmHg vs. 135.29 ± 15.59 mmHg) and the mean DBP (77.41 ± 9.06 mmHg vs. 91.18 ± 8.86 mmHg) were significantly decreased in the hypertensive group of patients at the follow-up (P < 0.05). For the normotensive patients, they were maintained in the normal range (P > 0.05). The negative correlations of SBP (R = −0.12, P > 0.05) and DBP (R = −0.32, P < 0.05) changes with VO2maxchange were found. Conclusion: IRP increased the VO2maxand reduced the BP in IHD patients with elevated BP. The reduction in BP correlated with an increase in VO2maxin IHD patients.