RNA Signaling In Microenvironment

Various forms of RNAs exist in the extracellular vesicles, which are mRNA, microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and RNAs These RNAs in extracellular vesicles play important roles in intercellular RNA signaling. Inter- and intra-cellular travel of RNAs in cancer microenvironment LncRNAs in exosomes mediate cell-to-cell communication in cancer microenvironment affecting tumor Abstract RNA signaling has emerged to be focused in several diseases. Multiple types of RNAs including microRNA, long non-coding RNA, and circular RNA mediate the signals among cells in cancer microenvironment. These RNAs travel in the microenvironment via extracellular vesicles or exosomes. The messages carried by RNAs transactivate the cells in different organs, which may cause cancer metastasis or the amplification of diseases. Intercellular RNA signaling in microenvironment is of interest.