Silvia Turroni , Stephanie Wright , Simone Rampelli , Patrizia Brigidi , Pier Luigi Zinzani , Marco Candela
{"title":"微塑料塑造了人类胃肠道的生态","authors":"Silvia Turroni , Stephanie Wright , Simone Rampelli , Patrizia Brigidi , Pier Luigi Zinzani , Marco Candela","doi":"10.1016/j.cotox.2021.09.006","DOIUrl":null,"url":null,"abstract":"<div><p>Microplastic particles are global pollutants which have been measured in drinking water, dust, and some food items. Concerns about population exposures and the resulting risks to human health are increasing. Because the gut can be considered one of the primary sites for microplastic exposure in the human body, here, we explore the possible impact of ingested microplastic particles on gastrointestinal ecology, providing some evidence for their active role as a driver of dysbiotic variation in the human gut microbiome. This further stresses the urgent need to quantitatively assess both oral exposure and hazards of microplastic in the human gut, enabling prediction of the levels of microplastic risk and outcomes of dysbiotic changes in the gut microbiome to be inferred.</p></div>","PeriodicalId":37736,"journal":{"name":"Current Opinion in Toxicology","volume":"28 ","pages":"Pages 32-37"},"PeriodicalIF":6.1000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Microplastics shape the ecology of the human gastrointestinal intestinal tract\",\"authors\":\"Silvia Turroni , Stephanie Wright , Simone Rampelli , Patrizia Brigidi , Pier Luigi Zinzani , Marco Candela\",\"doi\":\"10.1016/j.cotox.2021.09.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Microplastic particles are global pollutants which have been measured in drinking water, dust, and some food items. Concerns about population exposures and the resulting risks to human health are increasing. Because the gut can be considered one of the primary sites for microplastic exposure in the human body, here, we explore the possible impact of ingested microplastic particles on gastrointestinal ecology, providing some evidence for their active role as a driver of dysbiotic variation in the human gut microbiome. This further stresses the urgent need to quantitatively assess both oral exposure and hazards of microplastic in the human gut, enabling prediction of the levels of microplastic risk and outcomes of dysbiotic changes in the gut microbiome to be inferred.</p></div>\",\"PeriodicalId\":37736,\"journal\":{\"name\":\"Current Opinion in Toxicology\",\"volume\":\"28 \",\"pages\":\"Pages 32-37\"},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2021-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Toxicology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2468202021000498\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"TOXICOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468202021000498","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"TOXICOLOGY","Score":null,"Total":0}
Microplastics shape the ecology of the human gastrointestinal intestinal tract
Microplastic particles are global pollutants which have been measured in drinking water, dust, and some food items. Concerns about population exposures and the resulting risks to human health are increasing. Because the gut can be considered one of the primary sites for microplastic exposure in the human body, here, we explore the possible impact of ingested microplastic particles on gastrointestinal ecology, providing some evidence for their active role as a driver of dysbiotic variation in the human gut microbiome. This further stresses the urgent need to quantitatively assess both oral exposure and hazards of microplastic in the human gut, enabling prediction of the levels of microplastic risk and outcomes of dysbiotic changes in the gut microbiome to be inferred.
期刊介绍:
The aims and scope of Current Opinion in Toxicology is to systematically provide the reader with timely and provocative views and opinions of the highest qualified and recognized experts on current advances in selected topics within the field of toxicology. The goal is that Current Opinion in Toxicology will be an invaluable source of information and perspective for researchers, teachers, managers and administrators, policy makers and students. Division of the subject into sections: For this purpose, the scope of Toxicology is divided into six selected high impact themed sections, each of which is reviewed once a year: Mechanistic Toxicology, Metabolic Toxicology, Risk assessment in Toxicology, Genomic Toxicology, Systems Toxicology, Translational Toxicology.