应用多能干细胞综合治疗血管因子缺陷型勃起功能障碍

M. Klunnyk, I. Matiyashchuk, N. Sych, Andriy Sinelnyk, Miroshnykov Io, K. Sorochynska
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引用次数: 0

摘要

目的:研究含胚胎干细胞(FSCs)的联合治疗对不同成分勃起的影响。材料和方法:在2014-2015年期间,19例混合型勃起功能障碍和强制性血管因子的患者在EmCell细胞治疗中心进行药物学记录的研究。主要组(MG)和对照组(CG)患者的检查方案包括国际勃起功能指数(IIEF)问卷、尿液分析、总睾酮和游离睾酮测试、性激素结合球蛋白(SHBG)、游离雄激素指数(FAI)、血糖和糖化血红蛋白(HbA1c)测试、血脂检查、海绵状血管药理学检查、运用临床方法和状态-特质焦虑量表(STAI)和贝克抑郁量表(BDI)对勃起的皮质和间脑成分进行研究。结论:伐地那非与含有胎儿肝、脑和胎盘多能FSCs的冷冻悬浮液联合使用对勃起各成分均有良好的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complex Treatment of Erectile Dysfunction with Vascular Factor Deficitby Use of Pluripotent Fetal Stem Cells
Objective: To study the effect of combined therapy including fetal stem cells (FSCs) on different components of erections. Material and methods: During a period of 2014-2015 years 19 patients with mixed type erectile dysfunction and mandatory vascular factor documented by pharmacodopplerography were under study in Cell Therapy Center EmCell. The program of examination for patients in the Main Group (MG) and Control Group (CG) included the scales of International Index of Erectile Function (IIEF) questionnaire, urine analysis, tests for total and free testosterone, Sex Hormone Binding Globulin (SHBG), Free Androgen Index (FAI), blood glucose and glycosylated Hemoglobin (HbA1c) testing, lipidogram findings, pharmacodopplerography of cavernous vessels, study of cortical and diencephalon components of erection by use of clinical methods and the questionnaires of State-Trait Anxiety Inventory – (STAI) and Beck Depression Inventory (BDI). Conclusion: combined use of vardenafil and cryopreserved suspensions containing pluripotent FSCs extracted from fetal liver, brain and placenta promotes favorable effect on all components of erections.
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