麻风病中糖皮质激素的逆转反应

Serbian Journal of Dermatology and Venereology Pub Date : 2019-09-01 DOI:10.2478/sjdv-2019-0011

Renni Yuniati, M. Khrisna

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引用次数: 2

摘要

摘要麻风是由麻风分枝杆菌引起的一种疾病，它会导致患者的许多残疾。麻风病采用多种药物治疗方案；然而，这种疗法可能会引起患者的麻风病反应。麻风反应有几种类型：1型反应、2型反应和神经炎。1型反应主要发生在BB、BL和BT型麻风中，其特征是原有病变的恶化。根据世界卫生组织指南，这种反应的治疗是皮质类固醇治疗。本文将解释皮质类固醇治疗麻风病逆转反应的几个关键点，包括副作用和可用的替代疗法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Glucocorticoids in Leprosy Reversal reaction

Abstract Leprosy is a disease that is caused by Mycobacterium leprae which results in lots of disabilities in the patients. Leprosy is treated by multi-drug therapy regimen; however, this therapy might cause leprosy reactions in the patients. There are several types of lepromatous reaction: type 1 reaction, type 2 reaction and neuritis. Type 1 reaction mainly occurs in BB, BL and BT forms of leprosy and is characterized by exacerbation of preexisting lesions. The therapy of this reaction according to the WHO guideline is corticosteroid therapy. This article will explain several key points related to the corticosteroid therapy in leprosy reversal reactions, including the side effects and alternative therapies available.

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来源期刊

Serbian Journal of Dermatology and Venereology

自引率

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期刊介绍： Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.