补充蛋白质和多种维生素治疗老年肌肉减少症/肌肉减少性肥胖:文献综述

Gazeta Medica Pub Date : 2022-03-24 DOI:10.29315/gm.v9i2.552
D. Marques, Catarina Gomes, Rosa Vilares Santos
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引用次数: 0

摘要

Sarcopenia可以被描述为一种与不利结果相关的肌肉疾病。肌细胞性肥胖是指伴随着肌细胞减少和肥胖。治疗这些疾病的最佳方法仍未确定。我们的目标是回顾目前关于营养作为治疗这些疾病的治疗选择的知识。从医学数据库中获得的1024篇文章中,有9篇被纳入叙述性综述。单独补充维生素D与显著差异无关。蛋白质补充剂,特别是富含亮氨酸的蛋白质补充剂,在纳入的研究中被广泛使用,对肌肉质量等一些肌肉参数有潜在的益处。补充蛋白质对肌萎缩性肥胖的益处尚不清楚。纳入的研究在许多参数上存在显著的异质性。因此,仍然不可能得出明确有效的结论,然而富含亮氨酸的蛋白质补充剂可能是一个有趣的选择。还需要进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Protein and Multivitamin Supplementation in Managing Sarcopenia/Sarcopenic Obesity in the Elderly: A Narrative Review of Literature
Sarcopenia may be described as a muscular disease associated with unfavourable outcomes. Sarcopenic obesity refers to the concomitant presence of sarcopenia and obesity. The best approach to these pathologies is still not determined. Our goal was to review the current knowledge regarding nutrition as a therapeutic option in the treatment of these conditions. From a total of 1024 articles obtained from medical databases, nine were included in the narrative review. Supplementation of vitamin D alone was not associated with significant differences. Protein supplements, especially those rich in leucine, have been commonly used in the included studies, with potential benefit in some muscle parameters such as muscle mass. Benefits of supplementation in sarcopenic obesity are less clear. There was significant heterogeneity between the included studies in many parameters. Therefore, clear and valid conclusions are still not possible, however leucine enriched protein supplements might be an interesting option. Further research is needed.
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