治愈心脏:释放基因疗法在心血管疾病治疗中的革命性潜力

Q4 Biochemistry, Genetics and Molecular Biology

Biochemist Pub Date : 2023-08-23 DOI:10.1042/bio_2023_129

A. Beqqali, A. Baker

{"title":"治愈心脏:释放基因疗法在心血管疾病治疗中的革命性潜力","authors":"A. Beqqali, A. Baker","doi":"10.1042/bio_2023_129","DOIUrl":null,"url":null,"abstract":"In medical science, few areas hold as much promise and excitement as gene therapy. It is a cutting-edge field that aims to harness the body’s own genetic machinery to combat diseases at their root cause. While gene therapy has shown potential across various diseases (notably in rare monogenetic disease areas), here we dive into the latest advancements specifically focused on the heart. With cardiovascular diseases remaining a leading cause of global morbidity and mortality, researchers are tirelessly exploring innovative ways to tackle rare and common heart-related ailments. In this article, we discuss the fascinating world of gene therapy, exploring recent breakthroughs as well as remaining challenges and their implications for cardiovascular health.","PeriodicalId":35334,"journal":{"name":"Biochemist","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Healing hearts: unlocking the potential of gene therapy in revolutionizing cardiovascular disease treatment\",\"authors\":\"A. Beqqali, A. Baker\",\"doi\":\"10.1042/bio_2023_129\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In medical science, few areas hold as much promise and excitement as gene therapy. It is a cutting-edge field that aims to harness the body’s own genetic machinery to combat diseases at their root cause. While gene therapy has shown potential across various diseases (notably in rare monogenetic disease areas), here we dive into the latest advancements specifically focused on the heart. With cardiovascular diseases remaining a leading cause of global morbidity and mortality, researchers are tirelessly exploring innovative ways to tackle rare and common heart-related ailments. In this article, we discuss the fascinating world of gene therapy, exploring recent breakthroughs as well as remaining challenges and their implications for cardiovascular health.\",\"PeriodicalId\":35334,\"journal\":{\"name\":\"Biochemist\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochemist\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1042/bio_2023_129\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Biochemistry, Genetics and Molecular Biology\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemist","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1042/bio_2023_129","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}

引用次数: 0

摘要

在医学科学中，很少有领域能像基因治疗那样充满希望和激动人心。这是一个前沿领域，旨在利用人体自身的基因机制，从根源上对抗疾病。虽然基因疗法已经在各种疾病(特别是罕见的单基因疾病领域)中显示出潜力，但在这里，我们将深入研究专门针对心脏的最新进展。由于心血管疾病仍然是全球发病率和死亡率的主要原因，研究人员正在不知疲倦地探索解决罕见和常见心脏相关疾病的创新方法。在这篇文章中，我们讨论了基因治疗的迷人世界，探索了最近的突破以及仍然存在的挑战及其对心血管健康的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Healing hearts: unlocking the potential of gene therapy in revolutionizing cardiovascular disease treatment

In medical science, few areas hold as much promise and excitement as gene therapy. It is a cutting-edge field that aims to harness the body’s own genetic machinery to combat diseases at their root cause. While gene therapy has shown potential across various diseases (notably in rare monogenetic disease areas), here we dive into the latest advancements specifically focused on the heart. With cardiovascular diseases remaining a leading cause of global morbidity and mortality, researchers are tirelessly exploring innovative ways to tackle rare and common heart-related ailments. In this article, we discuss the fascinating world of gene therapy, exploring recent breakthroughs as well as remaining challenges and their implications for cardiovascular health.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Biochemist Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： This lively and eclectic magazine for all life scientists appears six times a year. Its quirky style and astute selection of serious and humorous articles ensures that the magazine"s appeal is by no means restricted to that of the avid biochemist. Specially commissioned articles from leading scientists bring a popular science perspective direct to you! Forthcoming themes include: RNAi, Money in Science, Extremophiles, Biosystems and Mathematical Modelling, Renascence of Mitochondria, Prions & Protein factors, Imaging live cells and Model organisms.