CT引导下活检、穿刺和引流的剂量变化:一项全国1709例患者的调查

Laure Berny , Joël Greffier , Chris Serrand , Djamel Dabli , Fabien De Oliveira , Hélène de Forges , Jean-Paul Beregi , Julien Frandon
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引用次数: 0

摘要

背景最近一项全国性研究公布了5001名患者在CT引导下进行主要介入治疗的剂量参考水平。我们评估了患者的年龄、性别和靶器官对胸腹盆腔活检和穿刺/引流过程中患者剂量的影响。患者和方法数据取自先前的全国性研究。2017年1月至2019年6月期间,在所有参与中心进行的所有胸部或腹部骨盆部位的活检、穿刺和引流都包括在研究中。使用剂量-长度乘积(DLP)对数的线性回归进行多变量分析,并根据年龄、性别、解剖位置、螺旋采集次数和纳入中心进行调整。结果在最初研究的5001名患者中,2383人受益于胸部或腹部骨盆手术,其中674例经皮破坏除外。1709名患者(44个中心),1045名男性,664名女性,中位年龄64.4±14.0岁。平均DLP为751.2±642.7mGy.cm。男性的DLP显著高于女性(p=0.0005),腹盆腔手术的DLP明显高于胸部手术(p<0.0001)。结论在CT指导下进行腹部和胸部活检和穿刺/引流的患者剂量取决于性别和位置。进一步的研究考虑了患者的形态和手术的解剖位置,可以提出更精细的剂量参考水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dose variations for biopsy, puncture and drainage under CT guidance: A national survey in 1709 patients

Background

A nation-wide study recently published the dose reference levels for the main CT-guided interventional procedures in 5001 patients. We assessed the impact of patient's age, sex and targeted organ on the patient dose during thoracic and abdominopelvic biopsies and punctures/drainages.

Patients and methods

Data were extracted from the previous nationwide study. All biopsies, punctures and drainages for thoracic or abdominopelvic locations performed between January 2017 and June 2019 in all participating centers were included in the study. Multivariable analyses were carried out using a linear regression of the dose-length product (DLP) log, adjusted to age, sex, anatomical location, number of helical acquisitions and inclusion center.

Results

Of the 5001 patients of the initial study, 2383 benefited from thoracic or abdominopelvic procedures, including 674 percutaneous destructions excluded. 1709 patients (44 centers), 1045 men, 664 women, median age 64.4 ± 14.0 years were included. The mean DLP was 751.2 ± 642.7mGy.cm. It was significantly higher in men than women (p = 0.0005) and higher for abdominopelvic procedures than for thoracic locations (p<0.0001).

Conclusion

Doses delivered to patients for abdominal and thoracic biopsies and punctures/drainages performed under CT guidance depend on gender and location. Furthers studies taking into account the patient's morphology and anatomical location of the procedure would allow proposing finer dose reference levels.

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