老年妇女猫抓致角膜棘瘤1例

Alawami Az, Elberg Jj, Tannous Zs
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引用次数: 0

摘要

背景:角斑蝥瘤是一种相对常见的自限性鳞状细胞增生。它们是鳞状细胞癌的变体还是良性肿瘤,这是一个有争议的问题。确切的病因尚不确定,但据信是多因素的,据报道与创伤有关。本报告描述了一位患有多发性角化棘皮瘤的老年妇女在被宠物猫抓伤的部位发展。方法:一例92岁的阿尔茨海默病患者,其左腿出现多处快速生长、外观怪异的病变。病变出现在被猫抓伤几周后。结果:细菌、真菌和非典型分枝杆菌的组织培养均为阴性。组织病理学检查与角化棘皮瘤一致。结论:角斑蝥瘤的发生与光化损伤、遗传易感性、致癌物、免疫抑制和病毒有关。角化棘皮瘤似乎也更倾向于既往有创伤的部位。我们的病例进一步证明了创伤和角化棘皮瘤密切相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Keratoacanthomas Induced by Cat Scratches in an Elderly Woman
Background: Keratoacanthomas (KAs) are relatively common self-limited squamous proliferations. It is a matter of debate, whether they are a variant of squamous cell carcinoma or benign neoplasms. The exact etiology is uncertain, but is believed to be multifactorial, and is reportedly associated with trauma. This report describes an elderly woman with multiple keratoacanthomas developing at sites scratched by a pet cat. Methods: A case of a 92-year-old woman with Alzheimer’s disease, presented with multiple rapidly growing, bizarre looking lesions on the left leg. The lesions appeared several weeks after being scratched by a cat. Results: Tissue cultures for bacteria, fungi and atypical mycobacteria were negative. Histopathologic examination was consistent with keratoacanthoma. Conclusion: The development of Keratoacanthomas (KAs) have been associated with actinic damage, genetic susceptibility, carcinogens, immunosuppression and viruses. It also seems that keratoacanthoma has predilection for sites with previous trauma. Our case is a further evidence that trauma and keratoacanthoma are closely related.
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