儿童头颈部恶性肿瘤的发病模式

Pub Date : 2020-07-01 DOI:10.4103/jhnps.jhnps_21_20
V. Mungutwar, Manya Thakur, Harbans Singh, Sushma Singh, D. Hota
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引用次数: 0

摘要

背景:与成人不同,头颈部恶性肿瘤在儿童期并不常见,它也导致儿童癌症总发病率较低。印度的这一数字最近一直在增加。因此,我们进行了一项研究,以了解0-18岁年龄组住院患者的头颈癌模式。目的:研究转诊医院中儿童年龄组(<18岁)不同类型头颈部恶性肿瘤的发病模式。主题和方法:我们在我们的三级护理中心对儿童头颈部恶性肿瘤进行了一项观察性研究。所有0-18岁年龄组的儿童都被纳入了这项研究。共有72例病例是从医院处理儿科患者的各个部门进行回顾性和前瞻性研究的。结果:我们的研究共包括72例病例,其中21例为颈部继发的急性淋巴细胞白血病,其次是颈部继发的9例急性髓系白血病。鼻咽和腮腺癌共8例;霍奇金/非霍奇金淋巴瘤合并颈部淋巴结15例。病例数最少的是下颌骨癌、伯基特淋巴瘤和伴有继发性颈淋巴结的慢性粒细胞白血病。大多数病例表现为右侧颈部肿块或淋巴结病。男女比例均为1.78:1。大多数病例是通过骨髓穿刺活检、细针穿刺细胞学或切除活检诊断的。结论:恶性肿瘤是儿童颈部肿块的一种鉴别诊断方法。血液系统恶性肿瘤和淋巴瘤仍然是儿童年龄组头颈癌的两个主要原因。
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Pattern of Head-and-Neck Malignancies in the Pediatric Population
Background: Head-and-neck malignancies are uncommon in childhood unlike in adults, also it contributes to low proportion of overall cancer incidence among children. The number in India has been increasing in the recent past. Hence, we conducted a study to know the pattern of head-and-neck cancers in hospitalized patients of 0–18 years’ age group. Aim: The aim was to study the pattern of different types of head-and-neck malignancies in the pediatric age group (<18 years) in a referral hospital. Subject and Methods: We have conducted an observational study of pediatric head-and-neck malignancies in our tertiary care center. All children in the age group of 0–18 years were included in the study. A total of 72 cases were taken retrospectively and prospectively from various departments of hospital which deal with pediatric patients. Results: Our study comprises total 72 cases, maximum cases were of acute lymphocytic leukemia with secondaries in neck n = 21, followed by 9 cases were of acute myeloid leukemia with secondaries in the neck. Carcinomas of the nasopharynx and parotid both were 8 in number; 15 cases were of Hodgkin/non-Hodgkin lymphoma with involvement of neck nodes. The least number of cases was of carcinoma mandible, Burkitt lymphoma, and chronic myeloid leukemia with secondary neck nodes. Most cases presented with right-sided neck mass or lymphadenopathy. Male-to-female ratio was 1.78:1 in all cases. Most of the cases were diagnosed either by bone marrow aspiration biopsy, fine-needle aspiration cytology, or excisional biopsy. Conclusion: Malignancy is one of the differentials of pediatric neck masses. Hematological malignancies and lymphomas are still two major contributors of head-and-neck cancers in the pediatric age group.
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