维生素D2和维生素D3是骨骼健康受损的风险因素

Chiril Voloc, Aliona Rotari, A. Voloc, E. Kuissi Kamgaing, J. F. Djoba Siawaya, S. Ategbo
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引用次数: 0

摘要

背景:维生素D在预防多种疾病中发挥着重要作用。全世界有超过10亿人患有维生素D缺乏症。维生素D缺乏会导致16种癌症(乳腺癌、结肠癌、前列腺癌等)、心血管疾病、中风、自身免疫性疾病、牙周疾病、肺泡内手术移植失败等。有几个危险因素会阻碍治疗目标的实现。预防缺乏性佝偻病的国家方案优先考虑维生素D2而不是维生素D3,这对儿童和成人的口腔健康造成了医疗风险因素。这篇文章提供了充足的论据,支持维生素D3和维生素D2处方预防和治疗的目的。结论:考虑到维生素D缺乏目前是一个全球性的公共卫生问题,可以建议将维生素D缺乏列为国家一级的优先公共卫生问题。维生素D3应该是选择性的,以防止缺乏。考虑到与维生素D缺乏有关的急慢性疾病众多,为了提高维生素D在所有人口类别中的地位,有必要将维生素D3列入国家全额补贴的分子清单,并至少免费分发给5岁以下儿童和处于集约生长时期的青少年。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin D2 versus vitamin D3 as a risk factor in compromised bone health
Background: Vitamin D plays an important role in the prevention of many diseases. More than 1 billion people worldwide suffer from vitamin D deficiency. Vitamin D deficiency can contribute to the development of 16 types of cancer (breast, colon, prostate, etc.), cardiovascular diseases, stroke, autoimmune diseases, periodontal pathologies, transplant failure in endo-alveolar surgery, etc. There are several risk factors that would prevent the achievement of treatment objectives. The national protocol for deficiency rickets prevention privileges vitamin D2 versus vitamin D3, which creates a medical risk factor compromising oral health in both children and adults. The article provides sufficient arguments in favour of vitamin D3 vs vitamin D2 prescription for prophylactic and treatment purposes. Conclusions: Considering that vitamin D deficiency is currently a global public health problem, it can be proposed to declare vitamin D deficit/deficiency a priority public health problem at the national level. Vitamin D3 should be elective in preventing deficit. Taking into account the multitude of acute and chronic diseases related to vitamin D deficiency, in order to improve the status of vitamin D in all population categories, it is necessary to include vitamin D3 in the list of molecules fully subsidized by the state and distributed free of charge at least to children under the age of 5 years and adolescents in the period of intensive growth.
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