急性扁桃体炎细菌对抗生素敏感性的变化

Brihaspati Sigdel, S. Regmi
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引用次数: 1

摘要

更正:第二作者Sanjib Mani Regmi于2021年8月13日被添加到网站版本。它被错误地遗漏了。这篇文章的PDF格式是正确的。背景:扁桃体感染可能是上呼吸道感染的主要或继发的结果,通常在病毒感染之前发生。细菌性扁桃体炎最常由化脓性链球菌引起。盘尼西林仍然是治疗化脓性链球菌扁桃体炎的首选。本研究旨在鉴定急性扁桃体炎病原菌及其对抗生素的敏感性。材料与方法:本前瞻性研究于2018年1月至2019年1月在尼泊尔博卡拉Gandaki医学院耳鼻喉头颈外科和微生物科进行。96名因急性扁桃体炎入院的患者被纳入研究。结果:急性扁桃体炎以21 ~ 30岁年龄组最为常见。化脓性葡萄球菌32株(33.3%)最常见,其次是金黄色葡萄球菌19株(19.8%)。化脓性链球菌对氨苄西林和氯西林敏感(65.6%),对左氧氟沙星和多西环素敏感(68.7%)。碳青霉烯类药物是最有效的静脉治疗药物。结论:最常见的细菌是化脓性链球菌。微生物的敏感性从氨苄西林组转移到氟喹诺酮类药物和四环素。鉴定分离的细菌及其对抗生素的敏感性可以预防细菌对药物的耐药性,有助于对急性扁桃体炎进行适当的管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis
Correction: The second author, Sanjib Mani Regmi, was added to the website version on 13th August 2021. It omitted by mistake. The PDF of the article was correct. Background: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes. Penicillin remains the treatment of choice for S. pyogenes tonsillitis. The present study aimed to identify the bacterial pathogen in acute tonsillitis and their sensitivity to antibiotics. Material and Methods: This prospective study was conducted in the Department of Otolaryngology and Head & Neck Surgery and Department of Microbiology, Gandaki Medical College, Pokhara Nepal from January 2018 to January 2019. Ninety-six patients who presented with acute tonsillitis and admitted in the hospital were included in the study. Results: The commonest age group of acute tonsillitis was found to be between 21-30 years. S. pyogenes was the commonest isolate 32(33.3%) followed by S. aureus 19(19.8%).  Streptococcus pyogenes was sensitive to Ampicillin (65.6%) and Cloxacillin (68.7%) while the isolates were more sensitive to levofloxacin and doxycycline. Carbapenem were found to be most effective drugs for intravenous treatment. Conclusion: The most common bacterial isolates were Streptococcus pyogenes. The sensitivity of organism shift from ampicillin group to fluroquinolones and tetracycline. Identification of bacterial isolates and their antibiotics sensitivity patterns could prevent resistance of bacteria to drugs and help in the proper management of acute tonsillitis.
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