西马鲁肽:初级保健的战略武器

Akshay B. Jain
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摘要

2型糖尿病一直是全世界和新加坡长期关注的问题。作为东南亚糖尿病患病率最高的国家之一,新加坡已经探索了各种加强慢性疾病管理的方法,其中之一是在初级保健机构而不是专业机构治疗糖尿病患者。初级保健医生的任务是管理糖尿病患者的糖化血红蛋白水平,以及无数相关并发症,包括低血糖、心血管风险和体重问题。随着人群健康需求的日益复杂,口服西马鲁肽可以成为初级保健医生治疗2型糖尿病患者的战略武器。在控制血糖和减轻体重方面,口服西马鲁肽的效果优于其他几种口服抗糖尿病药物。此外,口服西马鲁肽已被证明具有心血管安全性和潜在益处。口服西马鲁肽的发展,而不是注射型,使患者更容易从西马鲁肽治疗中获益。口服西马鲁肽是2型糖尿病治疗的一种可行和有效的策略,无论是开始还是加强的需要,并且很好地定位为初级保健的游戏规则改变者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Semaglutide: A Strategic Weapon for Primary Care
Type 2 diabetes has been a long-standing concern worldwide and in Singapore. Having one of the highest diabetes prevalence rates in Southeast Asia, Singapore has explored various ways of enhancing the management of chronic illnesses, one of which is to treat diabetic patients in primary care settings rather than speciality facilities. Primary care physicians are tasked to manage their diabetic patients’ glycated haemoglobin levels, along with a myriad of related complications including hypoglycaemia, cardiovascular risk, and body weight issues. With the ever-increasing complexity of population health demands, oral semaglutide can be a strategic weapon utilised by primary care doctors to treat type 2 diabetic patients. In terms of glycaemic control and body weight reduction, oral semaglutide has outperformed several other oral anti-diabetic medicines. Moreover, oral semaglutide has a proven cardiovascular safety profile with potential benefits. The development of oral semaglutide, rather than the injectable type, has made it simpler for patients to benefit from semaglutide treatment. Oral semaglutide is a feasible and effective strategy in type 2 diabetes management, for both initiation and intensification needs, and is well positioned to be a game changer in primary care.
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