2016 - 2020年美国和加拿大病猪分离胸膜肺炎放线杆菌、支气管脓毒杆菌、多杀性巴氏杆菌和猪链球菌的药敏分析

IF 0.7 4区农林科学 Q3 Agricultural and Biological Sciences

Journal of Swine Health and Production Pub Date : 2022-05-02 DOI:10.54846/jshap/1282

M. Sweeney, Lacie A Gunnett, D. Mohan Kumar, B. Lunt, Lucina Galina Pantoja, D. Bade, Chandra M. Machin

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引用次数: 2

摘要

目的:报道2016 - 2020年美国和加拿大病猪分离的胸膜肺炎放线杆菌、支气管脓毒杆菌、多杀性巴氏杆菌和猪链球菌对动物用抗菌药物的体外敏感性。材料和方法:对10种抗菌药物(氨苄西林、头孢替弗、达诺沙星、恩诺沙星、氟苯尼考、青霉素、四环素、替尔米科星、甲氧苄啶-磺胺甲恶唑和土霉素)进行体外肉汤微量稀释药敏试验，对A型胸膜肺炎菌(n = 250)、B型支气管菌(n = 602)、P型多杀菌(n = 874)、和S suis (n = 1223)遵循临床和实验室标准协会批准的方法和药敏断点。结果:胸膜肺炎放线杆菌分离株对头孢替福、氟苯尼考、图拉霉素的敏感性为100%，P多毒杆菌分离株对头孢替福的敏感性为100%。A型胸膜肺炎对替尔米菌素的敏感性较高(95% ~ 99%);多毒菌为氨苄西林、恩诺沙星、氟苯尼考、青霉素、替米霉素和图拉霉素;S为氨苄西林和氟苯尼考;支气管杆菌对图拉霉素的反应。四环素对甲型胸膜肺炎(0% ~ 10.6%)、多杀性P(23.2% ~ 38.2%)和猪链球菌(0.8% ~ 2.1%)的敏感性较低。对氨苄西林无敏感性(0%)，对氟苯尼考的敏感性较低(3.9% ~ 15.2%)。意义:在本研究条件下，2016年至2020年期间在美国和加拿大收集的与猪呼吸系统疾病相关的主要病原体，胸膜肺炎A，支气管脓毒杆菌，多杀性P和猪链球菌，对大多数兽用抗菌药物表现出较高的敏感性。

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Antimicrobial susceptibility of Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Pasteurella multocida, and Streptococcus suis isolated from diseased pigs in the United States and Canada, 2016 to 2020

Objective: To report the in vitro susceptibility to veterinary antimicrobial agents of Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Pasteurella multocida, and Streptococcus suis isolated from diseased pigs in the United States and Canada from 2016 to 2020. Materials and methods: In vitro broth microdilution susceptibility testing for minimal inhibitory concentration values were performed using ten antimicrobial agents (ampicillin, ceftiofur, danofloxacin, enrofloxacin, florfenicol, penicillin, tetracycline, tilmicosin, trimethoprim-sulfamethoxazole, and tulathromycin) with A pleuropneumoniae (n = 250), B bronchiseptica (n = 602), P multocida (n = 874), and S suis (n = 1223) following methods and susceptibility breakpoints approved by the Clinical and Laboratory Standards Institute. Results: Actinobacillus pleuropneumoniae isolates were 100% susceptible to ceftiofur, florfenicol, and tulathromycin and P multocida isolates were 100% susceptible to ceftiofur. High rates of susceptibility (95% to > 99%) were observed for A pleuropneumoniae to tilmicosin; for P multocida to ampicillin, enrofloxacin, florfenicol, penicillin, tilmicosin, and tulathromycin; for S suis to ampicillin and florfenicol; and for B bronchiseptica to tulathromycin. Tetracycline exhibited low susceptibility rates against A pleuropneumoniae (0% to 10.6%), P multocida (23.2% to 38.2%), and S suis (0.8% to 2.1%). No susceptibility of B bronchiseptica to ampicillin (0%) and low rates of susceptibility to florfenicol (3.9% to 15.2%) were also observed. Implications: Under the conditions of this study, the predominant pathogens associated with swine respiratory disease in the United States and Canada, A pleuropneumoniae, B bronchiseptica, P multocida, and S suis collected during 2016 to 2020, display high rates of susceptibility to most veterinary antimicrobial agents.

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来源期刊

Journal of Swine Health and Production 农林科学-兽医学

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

>36 weeks

期刊介绍： The Journal of Swine Health & Production (JSHAP) is an open-access and peer-reviewed journal published by the American Association of Swine Veterinarians (AASV) since 1993. The aim of the journal is the timely publication of peer-reviewed papers with a scope that encompasses the many domains of applied swine health and production, including the diagnosis, treatment, management, prevention and eradication of swine diseases, welfare & behavior, nutrition, public health, epidemiology, food safety, biosecurity, pharmaceuticals, antimicrobial use and resistance, reproduction, growth, systems flow, economics, and facility design. The journal provides a platform for researchers, veterinary practitioners, academics, and students to share their work with an international audience. The journal publishes information that contains an applied and practical focus and presents scientific information that is accessible to the busy veterinary practitioner as well as to the research and academic community. Hence, manuscripts with an applied focus are considered for publication, and the journal publishes original research, brief communications, case reports/series, literature reviews, commentaries, diagnostic notes, production tools, and practice tips. All manuscripts submitted to the Journal of Swine Health & Production are peer-reviewed.