家族性高胆固醇血症伴腱黄瘤和跟腱炎——一个被遗忘的皮肤-风湿病学关联

Puspanjuli Sahu, S. Mohanan, C. Udayshankar, S. Sinhasan, R. Bhat
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引用次数: 0

摘要

家族性高胆固醇血症(FH)是一种具有皮肤病学和血液学表现的脂蛋白代谢紊乱。腱性黄瘤(TX)是该病的标志。它们与复发性肌腱炎和肌腱损伤有关,这是临床表现的一个方面,皮肤科医生对此并不熟悉。我们报告了两例杂合子家族性高胆固醇血症,患者在生命早期开始发展肌腱黄瘤,病变数量和大小逐渐增加。然而,他们出现较晚,只有当反复发作的肌腱炎变得严重。我们提出这些病例,以强调风湿病学特征,这可能是杂合家族性高胆固醇血症的第一症状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Familial Hypercholesterolemia with Tendinous Xanthomas and Achilles Tendinitis – A Forgotten Dermato-Rheumatologic Association
Abstract Familial hypercholesterolemia (FH) is a disorder of lipoprotein metabolism with dermatological and rhematological manifestations. Tendinous xanthomata (TX) are a hallmark of this disease. They are associated with recurrent tendinitis and tendon damage, an aspect of the clinical presentation, which is not well-known among dermatologists. We report two cases of heterozygous familial hypercholesterolemia, where the patients started developing tendinous xanthomata early in their life, with progressive increase in the number and size of lesions. However, they presented late, only when the recurrent attacks of tendinitis became severe. We present these cases to highlight the rheumatologic features, which may be the first symptom of heterozygous familial hypercholesterolemia.
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期刊介绍: Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.
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