对比增强液体衰减反转恢复(FLAIR)与对比增强T1 MRI在颅内肿瘤评估中的比较研究

Q4 Medicine

Rwanda Medical Journal Pub Date : 2022-12-31 DOI:10.4314/rmj.v79i4.4

Q. Hassan

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引用次数: 0

摘要

简介：在大多数机构，首选的对比MR序列是T1加权成像（T1WI）。目的：本研究旨在评价FLAIR对比增强与T1WI对比增强对颅内肿瘤的诊断价值，为进一步的临床判断提供数据。方法：对88例连续的颅内肿瘤进行对比增强脑MRI分析。FLAIR和T1以相等的百分比交替使用作为第一个对比增强序列，以避免病变的延迟对比增强效果。考虑了六个定量标准：病变与白质对比度（CR）和对比噪声比（CNR），病变与灰质对比度和CNR，以及病变与脑脊液对比度和CN。为了进行定性评估，两名经验丰富的放射科医生使用以下三个量表评估对比增强T1WI和FLAIR序列上的病变显著性：1，FLAIR优；2、序列相等；3、T1优。结果：在定量测量方面，对比度增强的FLAIR病变至白质、病变至脑脊液CR和CNR值在统计学上优于对比度增强T1加权图像（全部p=0.001）。然而，CE-FLAIR对灰质CR和CNR的损伤略高，但无统计学显著差异（分别为p=0.159和0.184）。对于定性评估，两位放射科医生都评估了对比度增强的FLAIR图像在评估病变显著性方面优于对比度增强T1加权图像，尤其是当它作为第二序列进行时。结论：FLAIR序列优于或可与T1序列相比较，尤其是当作为第二个对比后序列时。使用对比增强FLAIR作为常规MRI序列将提高诊断信心。

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Contrast-enhanced fluid-attenuated inversion-recovery (FLAIR) versus contrast-enhanced T1 MRI in the evaluation of intracranial tumors: A comparative study

INTRODUCTION: At most institutions, the favored contrast MR sequence is T1-weighted imaging (T1WI). However, lesion enhancement is occasionally inconspicuous on T1WI.Objective: This study aims to evaluate the diagnostic value of contrast-enhanced FLAIR compared to contrast-enhanced T1WI for intracranial tumors and to offer data for further clinical judgment. METHODS: 88 consecutive cases of intracranial tumors referred for contrast-enhanced brain MRI were analyzed. FLAIR and T1 were used alternately in equal percentages as the first contrast-enhanced sequence to avoid delayed contrast-enhancement effects of the lesions. Six quantitative criteria were considered: lesion-to-white matter contrast ratio (CR) and contrast-to-noise ratio (CNR), lesion-to-gray matter CR and CNR, and lesion-to-cerebrospinal fluid CR and CNR. For qualitative evaluation, two experienced radiologists assessed lesion conspicuity on contrast-enhanced-T1WI and FLAIR sequences using the following three scales: 1, FLAIR superior; 2, sequences equal; 3, T1 superior. RESULTS: For quantitative measurement, the contrast enhanced-FLAIR lesion-to-white matter, lesion-to-cerebrospinal fluid CR, and CNR values were statistically superior to those of the contrast enhanced-T1 weighted images (p = 0.001 in all). However, lesion-to-gray matter CR and CNR were slightly higher on CE-FLAIR, but with no statistically significant difference (p = 0.159, 0.184, respectively). For qualitative evaluation, both radiologists assessed that contrast enhanced-FLAIR images were superior to contrast enhanced-T1 weighted images for the evaluation of lesion conspicuity, especially when it was performed as the second sequence. CONCLUSION: FLAIR sequence was superior or comparable to T1 sequence, especially when performed as a second post-contrast sequence. Using contrast enhanced-FLAIR as a routine MRI sequence will increase diagnostic confidence.

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来源期刊

Rwanda Medical Journal Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

审稿时长

7 weeks

期刊介绍： The Rwanda Medical Journal (RMJ), is a Not-For-Profit scientific, medical, journal that is published entirely online in open-access electronic format. The RMJ is an interdisciplinary research journal for publication of original work in all the major health disciplines. Through a rigorous process of evaluation and peer review, The RMJ strives to publish original works of high quality for a diverse audience of healthcare professionals. The Journal seeks to deepen knowledge and advance scientific discovery to improve the quality of care of patients in Rwanda and internationally.