通过喷墨打印工艺制造用于分析应用的微流体纸基通道

IF 1.7 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY
N. N. Le, Duc Trinh-Minh Dinh, Phuong Hong Lam, Anh Van Thi Le, M. Le, Minh Duc Pham, Dung My Thi Dang, C. M. Dang
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引用次数: 0

摘要

微流控纸基通道在微流控纸基分析装置(μ pad)中起着重要的作用。在纸基上制备微流控通道有几种方法。其中,喷墨打印工艺具有成本低、节省材料、精度高等优点,被认为是一种很有前途的制造方法。本工作的目的是应用喷墨打印技术制备μ pad的纸通道。本文提出了一种新的μPAD设计方案,演示了如何利用喷墨打印的疏水线制作纸基生物传感器。我们的μPADs的生物学靶点是人绒毛膜促性腺激素(hCG)。用数码相机捕获μ pad的比色信号,用ImageJ软件测量,结果表明μ pad可以测定hCG在1000 ~ 10000 ng ml−1范围内的浓度。结果表明,压电喷墨打印技术可在纸基材上制备250 μm宽的疏水线,为后续μ pad的制备提供了技术支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fabrication of microfluidic paper-based channels by inkjet printing process for analytical applications
Microfluidic paper-based channels play an important role in microfluidic paper-based analytical devices (μPADs). There are some fabrication methods which could be utilised to fabricate microfluidic channels on paper substrate. Among these methods, inkjet printing process is considered as a promising fabrication method with many advantages such as low-cost, material saving, high precision, etc. The aim of this work is to apply inkjet printing technology to fabricate paper channels of μPADs. A new design of μPAD was proposed in this paper to demonstrate how to fabricate inkjet-printed hydrophobic lines to make paper-based biosensor. Biological target of our μPADs is human chOrionic gonadotropin (hCG). Colorimetric signals from μPADs were captured by digital camera and measured by ImageJ software, which showed that these μPADs can determine hCG in the range from 1,000 to 10,000 ng ml−1. These results showed that piezoelectric inkjet printing technology can fabricate 250 μm-width hydrophobic lines on paper substrate, helping in fabricating μPADs in next applications.
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来源期刊
Advances in Natural Sciences: Nanoscience and Nanotechnology
Advances in Natural Sciences: Nanoscience and Nanotechnology NANOSCIENCE & NANOTECHNOLOGYMATERIALS SCIE-MATERIALS SCIENCE, MULTIDISCIPLINARY
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