严重急性呼吸系统综合征冠状病毒2型检测在儿科人群中的重要性

Q4 Medicine
Rodica Demenciuc, L. Meliț, Tudor Fleșeriu, C. Mărginean
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引用次数: 0

摘要

与成人相比,儿童在SARS-CoV-2的症状差异方面存在多种特点,但无症状病例的发生率也更高。这些病例报告的目的是强调在儿科患者中进行SARS-CoV-2检测的重要性。第一个病例描述了一名2岁零9个月大的儿童因非自愿摄入有毒物质而被送入Targu Mures儿科诊所。临床检查发现咽部轻度充血,下颌骨下、颈侧及锁骨上方有小淋巴结;实验室检查发现白细胞增多、血小板增多、一种肝转氨酶高于正常限度。尽管存在表现方面的担忧,但该患者接受了SARS-CoV-2感染检测,结果为阳性。在入院期间,进化是有利的。第二例为3岁零8个月男患者,因怀疑异物吸入就诊于急诊科,但支气管镜检查仅发现气管和支气管内脓性分泌物。入院当天SARS-CoV-2感染的RTPCR检测为阴性,但由于病情发展缓慢,入院第5天重新检测,结果为阳性。对儿童患者进行独立于症状和临床环境的检测可能在限制病毒传播方面具有更高的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The importance of SARS-CoV-2 testing in pediatric population
Pediatric population associates multiple peculiarities in terms of SARS-CoV-2 regarding the differences of symptoms in comparison to adults, but also the higher incidence of asymptomatic cases. The aim of these case reports is to underline the importance of SARS-CoV-2 testing in pediatric patients. The first case describes the case of a 2-year and nine-month-old child admitted to the Pediatrics Clinic I Targu Mures for involuntary ingestion of toxic substance. The clinical exam pointed out a mild hyperemia of pharynx and small lymph nodes under the mandibula, on the side area of the neck and above the clavicula; and the laboratory tests pointed out leukocytosis, thrombocytosis and one of the liver transaminases above the normal limit. In spite of the presentation concerns, the patient was tested for SARS-CoV-2 infection, with positive result. The evolution was favorable during the admission. The second case describes a 3-year and 8-month-old male patient brought in the emergency department with the suspicion of foreign body aspiration, but the bronchoscopy revealed only purulent secretion in the trachea and bronchia. The RTPCR test for SARS-CoV-2 infection was negative on the admission day, but due to the slowly favorable evolution, the patient was retested on the 5th day of admission, with positive result. The testing of pediatric patients independently of the symptoms and the clinical setting might carry a higher importance in limiting the viral transmission.
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