2019-2021年Sergio E. Bernales国立医院实验室艾滋病毒载量监测的影响

Q4 Immunology and Microbiology
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引用次数: 0

摘要

本研究的目的是确定2019年至2021年期间在塞尔吉奥·贝纳莱斯国家医院实验室监测HIV病毒载量的影响。进行了描述性、定量、观察性、回顾性、比较性和分析性研究。我们对490名有随访病毒载量的患者进行了研究。调查结果显示,男性占主导地位,艾滋病毒感染者占64%,女性占36%。在监测期间,14.9%的患者作为新的艾滋病毒病例入院,8%的患者开始接受抗逆转录病毒治疗。关于病毒载量结果,14.9%的患者病毒载量大于1000拷贝/ml,5名患者的病毒载量在200至1000 cp/ml之间。70名患者的病毒载量大于40至≤1000 cp/mL,173名患者病毒载量小于40 cp/mL和174名患者的检测不到病毒载量。监测研究结束时,发现统计学显著性为0.00,Pearson相关系数为0.450,表明最终病毒载量与监测结果之间存在弱至中度相关性。这些发现强调了及时监测艾滋病毒患者病毒载量的至关重要性。有证据表明,在进行了充分病毒载量随访的患者中,38.3%的患者实现了病毒抑制,43.5%的患者保持了病毒抑制状态,14.9%的患者经历了病毒学失败,1%的患者出现了耐药性病毒血症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impacto en el monitoreo de carga viral de VIH en el laboratorio del Hospital Nacional Sergio E. Bernales 2019-2021
The objective of this study was to determine the impact of monitoring the HIV viral load in the Laboratory of the Sergio E. Bernales National Hospital during the period 2019 to 2021. A descriptive, quantitative, observational, retrospective, comparative, and analytical study was carried out. We worked with 490 patients who had follow-up viral load. The findings revealed a predominance of males with 64% of HIV cases and 36% of females. During the monitoring period, 14.9% of the patients were admitted as new HIV cases, while 8% started antiretroviral treatment (ART). Regarding the viral load results, 14.9% of the patients had a viral load greater than 1000 copies/ml, 5 patients had between 200 and 1000 cp/ml. 70 patients had a viral load greater than 40 to ≤ 1000 cp/mL, 173 patients had a viral load less than 40 cp/mL, and 174 patients had an undetectable viral load. At the end of the monitoring study, a statistical significance of 0.00 and a Pearson correlation coefficient of 0.450 were found, indicating a weak to moderate correlation between the final viral load and the monitoring result. These findings highlight the crucial importance of timely monitoring of viral load in patients with HIV. It was evidenced that 38.3% of the patients who had adequate viral load follow-up achieved viral suppression, 43.5% maintained viral suppression, 14.9% experienced virological failure, and 1% presented resistant viremia.
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来源期刊
Boletin De Malariologia Y Salud Ambiental
Boletin De Malariologia Y Salud Ambiental INFECTIOUS DISEASES-PARASITOLOGY
CiteScore
0.40
自引率
0.00%
发文量
51
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