银耳(真菌)提取物化妆品配方的组成优化

IF 3.4 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bartosz Woźniak, Jagoda Chudzińska, Paulina Szczyglewska, I. Nowak, Agnieszka Feliczak-Guzik
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引用次数: 0

摘要

根据最近的趋势,人们对以天然原料为基础的化妆品更感兴趣,已知对人体安全,包括从选定的植物中提取的提取物,富含活性成分,如蛋白质、维生素、微量和大量元素、磷脂、抗氧化剂和天然防腐剂。这种原料的一个例子是银耳提取物,它是透明质酸的天然替代品。它能保持皮肤细胞深处的水分,刺激皮肤对抗自由基,而自由基是导致皮肤过早衰老的原因。本研究的目的是在天然替代品的基础上优化化妆品配方的组成,以及它们的特性,包括物理化学和皮肤护理性能的测定。与不含银耳提取物的制剂相比,含银耳提取物的制剂可使TEWL降低12.4%,并使表皮得到充分的水合作用,这一点通过仪器方法得到了证实。此外,对获得的配方也进行了皮肤学测试,结果表明,在使用产品48和72小时后,任何测试志愿者都没有观察到红斑或肿胀/刺激。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimization of the Composition of a Cosmetic Formulation Containing Tremella fuciformis Extract (Fungi)
According to recent trends, people are more interested in cosmetic products based on natural raw materials, known to be safe for humans, including extracts obtained from selected plants, rich in active ingredients, such as proteins, vitamins, micro- and macro-elements, phospholipids, antioxidants, and natural preservatives. An example of such raw materials is Tremella fuciformis extract, which is a natural alternative to hyaluronic acid. It retains water deep in the skin cells and stimulates the skin to fight free radicals, which are responsible for the premature aging of the skin. The aim of this study was to optimize the composition of cosmetic formulations based on natural substitutes for the synthetic substances, as well as their characterization, which included the determination of the physicochemical and skin care properties. Formulations containing Tremella fuciformis extract had the effect of reducing TEWL by 12.4%, compared to a formulation that did not contain this active ingredient, and allowed adequate hydration of the epidermis, which was confirmed by apparatus methods. Additionally, dermatological tests were also conducted for the formulations obtained, which showed that no erythema or swelling/irritation was observed in any of the test volunteers 48 and 72 h after the application of the product.
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来源期刊
Cosmetics
Cosmetics Medicine-Surgery
CiteScore
5.20
自引率
12.10%
发文量
108
审稿时长
8 weeks
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