Andreea Calomfirescu-Avramescu, L. Ceauselu, Vlad Dima, Mihaela Demetrian, A. Bălănescu, P. Bălănescu, I. Gherghina
{"title":"一组足月新生儿缺氧缺血性脑病的胎盘变化","authors":"Andreea Calomfirescu-Avramescu, L. Ceauselu, Vlad Dima, Mihaela Demetrian, A. Bălănescu, P. Bălănescu, I. Gherghina","doi":"10.37897/rjp.2022.2.1","DOIUrl":null,"url":null,"abstract":"Objectives. The aim of this study was to present and describe specific macroscopic and microscopic placental findings in patients with hypoxic-ischemic encephalopathy (HIE). Materials and methods. We conducted an observational prospective study which included 84 patients diagnosed with HIE and had available placental histopathological examination. HIE diagnosis was performed according to Sarnat Score. Both macroscopic and microscopic placental lesions were identified. Patients were divided into 2 groups according to the presence of placental lesions. Outcomes. Placental lesions were associated with HIE. Patients with both HIE and placental lesions had lower pH value (p <0.001) and lower Apgar scores (p=0.001). Conclusion. Antenatal placental lesions are present in full-term infants with encephalopathy and seem to define exactly one of the causes of this syndrome.","PeriodicalId":33512,"journal":{"name":"Revista Romana de Pediatrie","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Placental changes in a group of full-term newborns with hypoxic-ischemic encephalopathy\",\"authors\":\"Andreea Calomfirescu-Avramescu, L. Ceauselu, Vlad Dima, Mihaela Demetrian, A. Bălănescu, P. Bălănescu, I. Gherghina\",\"doi\":\"10.37897/rjp.2022.2.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objectives. The aim of this study was to present and describe specific macroscopic and microscopic placental findings in patients with hypoxic-ischemic encephalopathy (HIE). Materials and methods. We conducted an observational prospective study which included 84 patients diagnosed with HIE and had available placental histopathological examination. HIE diagnosis was performed according to Sarnat Score. Both macroscopic and microscopic placental lesions were identified. Patients were divided into 2 groups according to the presence of placental lesions. Outcomes. Placental lesions were associated with HIE. Patients with both HIE and placental lesions had lower pH value (p <0.001) and lower Apgar scores (p=0.001). Conclusion. Antenatal placental lesions are present in full-term infants with encephalopathy and seem to define exactly one of the causes of this syndrome.\",\"PeriodicalId\":33512,\"journal\":{\"name\":\"Revista Romana de Pediatrie\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Romana de Pediatrie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37897/rjp.2022.2.1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Romana de Pediatrie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37897/rjp.2022.2.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Placental changes in a group of full-term newborns with hypoxic-ischemic encephalopathy
Objectives. The aim of this study was to present and describe specific macroscopic and microscopic placental findings in patients with hypoxic-ischemic encephalopathy (HIE). Materials and methods. We conducted an observational prospective study which included 84 patients diagnosed with HIE and had available placental histopathological examination. HIE diagnosis was performed according to Sarnat Score. Both macroscopic and microscopic placental lesions were identified. Patients were divided into 2 groups according to the presence of placental lesions. Outcomes. Placental lesions were associated with HIE. Patients with both HIE and placental lesions had lower pH value (p <0.001) and lower Apgar scores (p=0.001). Conclusion. Antenatal placental lesions are present in full-term infants with encephalopathy and seem to define exactly one of the causes of this syndrome.