异丙酚-丁托啡诺与异丙酚-芬太尼联合应用于骨科手术中喉罩气道不同插入条件的比较评价

M. Dwivedi, Anisha Puri, Sankalp Dwivedi, Gurchand Singh
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引用次数: 2

摘要

肩关节镜可在局部阻滞或全身麻醉下进行。全身麻醉使用喉罩气道(LMA)可以替代区域技术。在下咽内插入LMA需要足够的麻醉深度,以放松颌骨并抑制喉反射。各种辅助剂与诱导剂异丙酚联合使用,以改善LMA的插入条件,提高肩部手术的疼痛评分。目的:本研究的目的是比较肩关节镜下使用静脉(IV)布托啡诺或静脉芬太尼联合静脉异丙酚时LMA的插入条件和术后疼痛评分。方法:随机抽取各类择期手术患者100例,分为F组(丙泊酚+芬太尼)和B组(丙泊酚+丁托啡诺),每组50例。B组静脉滴注布托啡诺(30 μg/kg)共诱导,F组静脉滴注芬太尼(1.5 μg/kg)共诱导。共诱导1分钟后,静脉注射异丙酚2.5 mg/kg诱导,评估下颌松弛,并插入LMA。术后疼痛评分采用视觉模拟评分法(VAS)。结果:通过观察和分析,我们发现布托啡诺组的LMA插入条件明显更好(下颌松弛组[90% vs. 34%;P < 0.0001]和插入便利性[96%对66%;P = 0.0001])高于芬太尼。研究期间患者术后VAS平均评分比较,两组患者术后1 h VAS评分均较低,但B组VAS评分明显低于F组。F组患者术后2 h和4 h VAS平均评分较高,且以首次镇痛需求居多。结论:异丙酚-丁托啡诺联用比异丙酚-芬太尼联用具有更好的LMA插入条件。由于芬太尼和布托啡诺的镇痛作用,较低的VAS评分有助于肩关节镜患者的无痛移动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative assessment of the propofol-butorphanol with propofol-fentanyl combination for different insertion conditions of laryngeal mask airway in orthopedic surgery
INTRODUCTION: Shoulder arthroscopy can be performed under regional blocks or general anesthesia. General anesthesia using laryngeal mask airway (LMA) can be an alternative to regional techniques. Insertion of LMA within the hypopharynx mandates a depth of anesthesia apt enough to relax the jaw and obtund the laryngeal reflexes. Various adjuncts are combined with the induction agent propofol to facilitate improved insertion conditions of LMA and improved pain scores in shoulder surgeries. AIM: The aim of this study was to a comparison of insertion conditions of LMA and postoperative pain scores in shoulder arthroscopies using either intravenous (IV) butorphanol or IV fentanyl in combination with IV propofol. METHODS: A total of 100 patients scheduled for various elective surgical procedures were randomly selected and divided into two groups of 50 each, that is, Group F (propofol and fentanyl) and Group B (propofol and butorphanol). Coinduction was done in Group B with IV butorphanol (30 μg/kg) and in Group F with IV fentanyl (1.5 μg/kg). One minute after coinduction, the induction was achieved with IV propofol 2.5 mg/kg, jaw relaxation was assessed, and LMA was inserted. The postoperative pain scoring was done with visual analog scale (VAS). RESULTS: With the observations made and analyzed, we found that the LMA insertion conditions were significantly better with butorphanol (jaw relaxation [90% vs. 34%; P < 0.0001] and ease of insertion [96% vs. 66%; P = 0.0001]) than fentanyl. Comparison of average VAS score of patients postoperatively during the study showed low VAS score in both groups at 1 h, but Group B showed significantly lower score as compared to Group F. Group F showed a higher mean score of VAS at 2 h and 4 h and signified first analgesic need in the majority. CONCLUSION: The use of propofol-butorphanol combination produces excellent LMA insertion conditions as compared to propofol-fentanyl combination. Lower VAS scores due to analgesic effects of fentanyl and butorphanol contribute to painless shifting of patients undergoing shoulder arthroscopy.
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