使用功能神经成像进行自闭症分类的深度学习

S. Ryali
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摘要

深度学习模型推动了科学的许多分支。然而,这些模型尚未充分开发用于神经成像应用,主要是因为无法获得大型标记数据集。在这项研究中,我们提出了一种可解释的深度学习方法来研究自闭症谱系障碍(ASD)的神经生物学,ASD是最常见的神经发育障碍之一。我们的方法在区分ASD和典型受试者方面实现了最先进的分类准确性,并确定了大脑特征,最终确定了预测症状严重程度的特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Deep Learning for the Classification of Autism Using Functional Neuroimaging
Deep learning models have advanced many branches of science. However, these models have not been adequately developed for neuroimaging applications mainly because of the non-availability of large labelled datasets. In this study, we present an explainable deep learning approach to investigate the neurobiology of the autism spectrum disorder (ASD), which is one of the most prevalent neurodevelopmental disorders. Our approach achieved state of the art classification accuracy and identified brain features in discriminating ASDs from the typical subjects and finally identified features that predicted the severity of the symptoms.
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