如何减少COVID-19大流行相关评估参数对定量感染风险的误读

Q4 Medicine
J. Rassow
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引用次数: 0

摘要

简介:新冠肺炎大流行中感染风险的定量信息目前仅根据每日新增感染者计算,每日新增感染仅占100%传染性急性感染的6.60%±1.34%,因此与感染风险不成比例。这里提供的所有方法和结果都是针对德国的数据显示的,但可以转移到世界各地的任何其他地区。方法:目前使用的更精确的参数是基于急性感染:这里建议了压力指数,包括与卫生系统压力极限的距离、感染源的密度以及过去5天急性感染的变化。结果:当前和新的评估参数的结果比较表明,每日新增感染人数的大幅波动高达±22%,会导致不必要的不确定性。新的评估参数相应地更加精确。德国法律于2020年11月和2021年4月引入的7天发病率预警阈值是根据新感染病例确定的。因此,由于7天发病率值的大幅波动高达±23%,可能会错误地评估真正的感染风险,因此,如果法律规定的保护措施在客观上不合理或出台太迟,可能会产生法律冲突。结论:通过将新感染转移到急性感染作为计算基础,可以更准确地描述感染风险,甚至可以避免不合理、昂贵的保护措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How to Reduce Misinterpretation of Quantitative Infection Risk by Assessment Parameters Associated with the COVID-19 Pandemic
Introduction: The quantitative information on the risk of infection in the COVID-19 pandemic is calculated currently exclusively on the base of new infections per day, which only contribute 6.60%±1.34% to the 100% contagious acute infections and are, therefore, not proportional to the risk of infection. All methods and results presented here are shown for data in Germany, but can be transferred to any other region worldwide. Methods: More precise parameters as are used at present, are based on acute infections: stress index with information about the distance to the stress limit of the health system, the density of the sources of infection and the change in acute infections during the last 5 days are suggested here. Results: The comparison of the results of the current and the new assessment parameters shows that large daily fluctuations in new infections of up to ±22% lead to unnecessary uncertainties. The new assessment parameters are correspondingly more precise. The 7-days incidence warning thresholds introduced by German law in November 2020 and April 2021 are defined on the base of new infections. As a result, the real infection risks can be incorrectly assessed due to the large fluctuations of the 7-days incidence values up to ±23%, so that legal conflicts can arise if legally prescribed protective measures are objectively unjustified or introduced too late. Conclusion: By moving from new infections to acute infections as a base for calculation, infection risks can be described more precisely and even unjustified, expensive protective measures can be avoided.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
26
审稿时长
12 weeks
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