Haoran Liu, Yile Fang, Xiangyi Su, Yue Wang, Minjie Ji, Hongbing Xing, Yuelei Gao, Yuanying Zhang, N. He
{"title":"基于改进的混合模糊比例积分微分(PID)控制的聚合酶链式反应(PCR)仪器温度控制算法","authors":"Haoran Liu, Yile Fang, Xiangyi Su, Yue Wang, Minjie Ji, Hongbing Xing, Yuelei Gao, Yuanying Zhang, N. He","doi":"10.1080/10739149.2022.2105866","DOIUrl":null,"url":null,"abstract":"Abstract Here is reported an adaptive polymerase chain reaction (PCR) temperature control algorithm based on improved hybrid fuzzy proportional integral derivative (PID) control. The algorithm adopts fuzzy control in the rapid temperature changing stage for monitoring and reduces the overshoot. In the constant temperature stage, the PID controller's initial parameters are automatically calculated online through the relay self-tuning algorithm. The output of the system is pre-compensated by feedforward compensation algorithm, and adjusted by the variable universe fuzzy PID algorithm, which avoids the explosion of fuzzy rules to a certain extent. The experimental results show that the average heating rate of the improved hybrid fuzzy PID control algorithm is 4.2 °C/s, with an average cooling rate is 3.2 °C/s. The system stabilizes within 5 s with a maximum overshoot of less than 1.2 °C and a static error of ± 0.1 °C at various ambient temperatures.","PeriodicalId":13547,"journal":{"name":"Instrumentation Science & Technology","volume":"51 1","pages":"109 - 131"},"PeriodicalIF":1.3000,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Temperature control algorithm for polymerase chain reaction (PCR) instrumentation based upon improved hybrid fuzzy proportional integral derivative (PID) control\",\"authors\":\"Haoran Liu, Yile Fang, Xiangyi Su, Yue Wang, Minjie Ji, Hongbing Xing, Yuelei Gao, Yuanying Zhang, N. He\",\"doi\":\"10.1080/10739149.2022.2105866\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Here is reported an adaptive polymerase chain reaction (PCR) temperature control algorithm based on improved hybrid fuzzy proportional integral derivative (PID) control. The algorithm adopts fuzzy control in the rapid temperature changing stage for monitoring and reduces the overshoot. In the constant temperature stage, the PID controller's initial parameters are automatically calculated online through the relay self-tuning algorithm. The output of the system is pre-compensated by feedforward compensation algorithm, and adjusted by the variable universe fuzzy PID algorithm, which avoids the explosion of fuzzy rules to a certain extent. The experimental results show that the average heating rate of the improved hybrid fuzzy PID control algorithm is 4.2 °C/s, with an average cooling rate is 3.2 °C/s. The system stabilizes within 5 s with a maximum overshoot of less than 1.2 °C and a static error of ± 0.1 °C at various ambient temperatures.\",\"PeriodicalId\":13547,\"journal\":{\"name\":\"Instrumentation Science & Technology\",\"volume\":\"51 1\",\"pages\":\"109 - 131\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2022-08-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Instrumentation Science & Technology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1080/10739149.2022.2105866\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Instrumentation Science & Technology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/10739149.2022.2105866","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Temperature control algorithm for polymerase chain reaction (PCR) instrumentation based upon improved hybrid fuzzy proportional integral derivative (PID) control
Abstract Here is reported an adaptive polymerase chain reaction (PCR) temperature control algorithm based on improved hybrid fuzzy proportional integral derivative (PID) control. The algorithm adopts fuzzy control in the rapid temperature changing stage for monitoring and reduces the overshoot. In the constant temperature stage, the PID controller's initial parameters are automatically calculated online through the relay self-tuning algorithm. The output of the system is pre-compensated by feedforward compensation algorithm, and adjusted by the variable universe fuzzy PID algorithm, which avoids the explosion of fuzzy rules to a certain extent. The experimental results show that the average heating rate of the improved hybrid fuzzy PID control algorithm is 4.2 °C/s, with an average cooling rate is 3.2 °C/s. The system stabilizes within 5 s with a maximum overshoot of less than 1.2 °C and a static error of ± 0.1 °C at various ambient temperatures.
期刊介绍:
Instrumentation Science & Technology is an internationally acclaimed forum for fast publication of critical, peer reviewed manuscripts dealing with innovative instrument design and applications in chemistry, physics biotechnology and environmental science. Particular attention is given to state-of-the-art developments and their rapid communication to the scientific community.
Emphasis is on modern instrumental concepts, though not exclusively, including detectors, sensors, data acquisition and processing, instrument control, chromatography, electrochemistry, spectroscopy of all types, electrophoresis, radiometry, relaxation methods, thermal analysis, physical property measurements, surface physics, membrane technology, microcomputer design, chip-based processes, and more.
Readership includes everyone who uses instrumental techniques to conduct their research and development. They are chemists (organic, inorganic, physical, analytical, nuclear, quality control) biochemists, biotechnologists, engineers, and physicists in all of the instrumental disciplines mentioned above, in both the laboratory and chemical production environments. The journal is an important resource of instrument design and applications data.