妊娠期肺动脉瘤的困境1例报告

Shadi Zamansaraei, Milad Nazari Sabet, Parvin Bahrami
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摘要

肺动脉动脉瘤(PAA),定义为肺动脉主壁扩张大于40mm,在女性和男性超过43 mm是一种罕见且致命的缺陷。由于有很高的破裂风险,特别是在有症状或严重扩张的情况下,建议手术干预。指南中并没有针对妊娠期肺动脉瘤直径的治疗方法提出建议。在这个罕见而独特的报告中,我们描述了一位26岁的孕妇,她之前有过生物肺瓣膜置换术的病史,在怀孕15周时,由于经胸超声心动图显示肺动脉主动脉瘤(55mm),她被转诊到心脏病和妊娠联合诊所。考虑到肺动脉直径和剥离的风险,我们告知其风险并建议其进行治疗性流产,但她拒绝了,好在妊娠期及几个月后的密切观察没有发生并发症。指南中并没有具体推荐基于妊娠肺动脉动脉瘤直径的治疗方法,但参考了主动脉瘤指南的建议,当PA直径> 5.5 cm时因夹层风险较高终止妊娠。确定妊娠期夹层风险时应考虑的其他因素包括:根据血管内PA压力高或低、PA直径增长速度和病因机制对PA动脉瘤进行分类。因此,如果怀孕,每个病人的决定将根据危险因素而有所不同
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Pulmonary Artery Aneurysm Dilemma in pregnancy: a Case Report
Pulmonary Artery Aneurysm (PAA), defined as greater than 40 mm dilation of the main pulmonary artery wall, in female and above 43 mm in males is a rare and fatal defect. Since there is a high risk for rupture, especially in cases of symptomatic or severe dilatation, surgical intervention is suggested. There is no recommendation about therapeutic methods based on the diameter of the pulmonary aneurysm in pregnancy in the guidelines. In this rare and unique report, we described a 26-year-old pregnant woman with previous history of biologic pulmonary valve replacement referred to the joint clinic of heart disease and pregnancy at 15 weeks of pregnancy because transthoracic echocardiography showed an aneurysm of the main pulmonary artery (55mm). Due to pulmonary artery diameter and risk of dissection, we informed her about the risks and recommended therapeutic abortion, but she refused and, fortunately no complication occurred during close observation in pregnancy and few months later. There is no specific recommendation about therapeutic methods based on the diameter of the pulmonary aneurysm in pregnancy in the guidelines, but referring to the aortic aneurysm guidelines recommendation, pregnancy termination when PA diameter > 5.5 cm because of the higher risk of dissection. Other factors should be considered to determine the risk of dissection in pregnancy include; categorized PA aneurysms to high or low intravascular PA pressure, PA diameter growth rate, and causative mechanisms. Thus, if pregnancy occurs, decisions about each patient will vary depending on risk factors
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