基于深度学习分类和多模态合成的脑磁共振图像分割

Q3 Medicine
R. Kala, P. Deepa
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引用次数: 0

摘要

准确检测脑肿瘤及其严重程度是医学领域的一项具有挑战性的任务。因此,有必要开发脑肿瘤检测算法,这是一个新兴的诊断,计划治疗和结果评估的算法。利用深度卷积神经网络,提出了一种基于深度学习分类和多模态组合的脑肿瘤分割方法。MRI的不同模式,如T1、flair、T1C和T2,作为所提出方法的输入。不同模态的MR图像按特定模态的信息内容比例使用。不同模态的权重按块计算,并将块的标准差作为块信息内容的代理。然后将T1、flair、T1C、T2MR图像的输入图像与T1、flair、T1C、T2图像的权值进行卷积。将磁共振图像的不同模态及其对应的权重进行卷积求和,得到新的合成图像,作为深度卷积神经网络的输入图像。深度卷积神经网络通过CNN的不同层进行分割,每层进行不同的滤波操作,得到增强的分类和分割的空间一致性结果。分析表明,该方法有效地结合了不同模态的判别信息,提高了分割的整体精度。利用brain tumor segmentation Challenge 2013数据库(BRATS2013)对所提出的深度卷积神经网络脑肿瘤分割方法进行了分析。完整区域、核心区域和增强区域用骰子相似系数和Jaccard相似度指标对挑战、排行榜和合成数据集进行验证。为了评价分类率,对准确率、精密度、灵敏度、特异性、分割不足、分割错误和分割过度等指标进行了评价,并与现有方法进行了比较。实验结果表明,与现有方法相比,该方法的分割精度更高。在这项工作中,深度卷积神经网络与不同模式的磁共振图像用于检测脑肿瘤。新的输入图像是通过卷积不同模态及其权重的输入图像来创建的。权重是使用块的标准偏差确定的。分割精度高,具有高效的外观和空间一致性。分割图像的评估完全通过使用完善的度量来评估。未来,我们将考虑和评估该方法与其他数据库的关系,并对存在不同类型噪声的分割精度结果进行分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Segmentation of Brain Magnetic Resonance Images using Deep Learning Classification and Multi-modal Composition
Accurate detection of brain tumor and its severity is a challenging task in the medical field. So there is a need for developing brain tumor detecting algorithms and it is an emerging one for diagnosis, planning the treatment and outcome evaluation. Brain tumor segmentation method using deep learning classification and multi-modal composition has been developed using the deep convolutional neural networks. The different modalities of MRI such as T1, flair, T1C and T2 are given as input for the proposed method. The MR images from the different modalities are used in proportion to the information contents in the particular modality. The weights for the different modalities are calculated blockwise and the standard deviation of the block is taken as a proxy for the information content of the block. Then the convolution is performed between the input image of the T1, flair, T1C and T2 MR images and corresponding to the weight of the T1, flair, T1C, and T2 images. The convolution is summed between the different modalities of the MR images and its corresponding weight of the different modalities of the MR images to obtain a new composite image which is given as an input image to the deep convolutional neural network. The deep convolutional neural network performs segmentation through the different layers of CNN and different filter operations are performed in each layer to obtain the enhanced classification and segmented spatial consistency results. The analysis of the proposed method shows that the discriminatory information from the different modalities is effectively combined to increase the overall accuracy of segmentation. The proposed deep convolutional neural network for brain tumor segmentation method has been analysed by using the Brain Tumor Segmentation Challenge 2013 database (BRATS 2013). The complete, core and enhancing regions are validated with Dice Similarity Coefficient and Jaccard similarity index metric for the Challenge, Leaderboard, and Synthetic data set. To evaluate the classification rates, the metrics such as accuracy, precision, sensitivity, specificity, under-segmentation, incorrect segmentation and over segmentation also evaluated and compared with the existing methods. Experimental results exhibit a higher degree of precision in the segmentation compared to existing methods. In this work, deep convolution neural network with different modalities of MR image are used to detect the brain tumor. The new input image was created by convoluting the input image of the different modalities and their weights. The weights are determined using the standard deviation of the block. Segmentation accuracy is high with efficient appearance and spatial consistency. The assessment of segmented images is completely evaluated by using well-established metrics. In future, the proposed method will be considered and evaluated with other databases and the segmentation accuracy results should be analysed with the presence of different kind of noises.
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来源期刊
CiteScore
1.70
自引率
0.00%
发文量
18
审稿时长
>12 weeks
期刊介绍: In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders. The journal publishes timely in-depth reviews, research article and drug clinical trial studies in the field of signal transduction therapy. Thematic issues are also published to cover selected areas of signal transduction therapy. Coverage of the field includes genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases. Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.
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