基因导向的酶前药物治疗:一种有希望的癌症治疗方法

A. Banerjee
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引用次数: 0

摘要

基因导向蛋白前药医疗辅助(GDEPT)可能是一种很有前途的策略,旨在通过表达一种编码副药催化剂的因子,将无毒前药转化为活化的细胞毒性剂,从而限制副药的一般毒性,改善治疗使用的性质。它为治疗某些癌症提供了一种全新的方法。脑癌和前列腺癌的临床试验已经完成,一些脑肿瘤的术后治疗的初始产品正在等待销售批准。最近的创新提供了一种全新的顺膜药物[1]的可行的未来发展的一瞥。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gene-Directed Enzyme Pro-drug Therapy: A Promising Way for Cancer Treatment
Gene-directed protein prodrug medical aid (GDEPT) may be a promising strategy that aims to limit the general toxicity associate degreed improve the property of therapy use through the expression of a factor that encodes associate degree catalyst that converts nontoxic prodrug into an activated cytotoxic agent. It offers a brand new approach to treating some cancers. Clinical trials are completed for brain and prostate cancers and also the initial product for post-surgical treatment of some brain tumors is awaiting selling approval. Recent innovations offer a glimpse into the doable future evolution of a brand new cistron medication [1].
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