罕见的大网膜多发性畸胎瘤和双侧卵巢巨大融合畸胎瘤一例报告并文献复习

Tingting Li, Wenli Zhang, Jingwen Huang, Yangmei Shen, T. Cui, A. Giannini, O. Tapisiz, R. Lasmar, B. Lasmar
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摘要

畸胎瘤通常在卵巢和/或附件上形成板状物或包围卵巢和(或)附件;然而,网膜畸胎瘤非常罕见,在近200年的时间里,只有46例被描述。在这里,我们报告了一位47岁的女性因间歇性胀痛和不适入院的病例。入院时,超声检查显示双侧附件区有一个不规则的囊性占位性病变。选择腹腔镜卵巢囊肿切除术作为治疗方案。但术中发现大网膜多发性畸胎瘤和2例大小超过20cm的巨大融合性双侧卵巢畸胎瘤并存,需要进行剖腹手术、子宫切除术、双侧输卵管切除术、大网膜切除术、阑尾切除术和肠溶术。手术三年后,尚未发现复发。我们报告了一例罕见的大网膜多发性畸胎瘤和双侧卵巢巨大融合畸胎瘤。组织病理学研究证实了畸胎瘤的诊断,手术完全解决了原有症状。网膜畸胎瘤没有标准的诊断标准或手术选择,这增加了误诊的可能性,也增加了适当手术的术前计划不足的可能性。超声波、CT、MRI以及可能的PET可能有助于诊断。在组织病理学检查后,必须区分成熟和未成熟畸胎瘤,才能做出明确诊断。尽管网膜畸胎瘤的恶性转化(MT)已有描述,但其风险非常罕见。手术切除网膜畸胎瘤是首选的治疗方法,大多数外科医生在腹腔镜下进行肿瘤切除。手术技术仍然特别重要,尤其是对年轻女性来说,最保守的方法对于保持生育能力和最大限度地减少手术发病率至关重要。处理取决于畸胎瘤的成熟度。对于成熟畸胎瘤,完全切除是可以治愈的,不需要进一步治疗。未成熟畸胎瘤具有潜在的恶性,因此患者可能需要化疗和
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rare multiple teratomas of the omentum and giant fused teratomas of the bilateral ovaries: a case report and review of the literature
Teratoma usually forms plates on or encompasses the ovaries and/or adnexa; however, teratomas of the omentum are so rare that only up to 46 cases have been described in nearly 200 years. Here, we report the case of a 47-year-old woman admitted to hospital with intermittent distending pain and discomfort. At the admission, an ultrasonic examination revealed an irregular cystic space–occupying lesion on the bilateral adnexa area. Laparoscopic ovarian cystectomy was selected as the treatment option. However, coexistence of multiple teratomas on the greater omentum and 2 giant, fused bilateral ovarian teratomas measuring over 20 cm were found during operation, thus needing laparotomy, hysterectomy, bilateral salpingooophenrectomy, omentectomy, appendicectomy, and enterolysis. Three years after the operation, no recurrence has yet been found. We report a rare case with multiple teratomas of the omentum and giant fused teratomas of the bilateral ovaries. Histopathological studies confirmed the diagnosis of teratomas, and surgery completely resolved the original symptoms. There are no standard diagnostic criteria or operative options for teratomas of the omentum, which increases the likelihood of misdiagnosis and of insufficient preoperative planning for the appropriate procedures. Ultrasound, CT, MRI and possibly also the PET may aid in the diagnosis. A definitive diagnosis is possible following histopathological examination, which must differentiate between mature and immature teratoma. Although, malignant transformation (MT) of the omentum teratoma has been described, the risk is very rare. Surgical excision of omentum teratoma is the treatment of choice, and most surgeons perform laparoscopy with tumor dissection. The surgical technique remains particularly important especially in young women, in whom the most conservative approach is crucial, to preserving fertility and minimizing surgical morbidity. The management depends upon the maturity of the teratoma. For mature teratoma, complete excision is curative and no further treatment is required. Immature teratomas are potentially malignant, so the patient may require chemotherapy and
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