哮喘和COVID-19

IF 0.3 Q4 ALLERGY
E. Çelebioğlu
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引用次数: 4

摘要

目的:强调本次大流行中的哮喘情况。描述患者和卫生专业人员的安全方面。讨论其严重程度,控制,危险因素,慢性疾病及其恶化的治疗管理。方法:收集新冠肺炎大流行背景下有关哮喘主题的科学文献资料。在PubMed数据库中进行了搜索,使用描述符:哮喘、冠状病毒感染、流行病、危险因素、药物治疗和肺活量测定。结果:哮喘尚未被确定为严重COVID-19疾病的重要危险因素,可能是由于特应性哮喘中血管紧张素转换酶受体的表达较低。研究发现,在严重哮喘患者中,这些受体的表达量更高。结论:应避免使用雾化器,不应共用间隔器,不建议使用肺活量测定或呼气峰流量测量。所有哮喘患者都应继续使用吸入性皮质类固醇。从12岁起不建议仅使用短效β - 2激动剂治疗。根据需要,低剂量吸入皮质类固醇与福莫特罗是该年龄组的首选缓解剂,可以在同一设备上一起提供。从6岁到11岁,缓解药物最好是短效β -受体激动剂,与低剂量吸入皮质类固醇相关,并在单独的设备中使用。在严重哮喘中,噻托溴铵应先于免疫生物学适应症,并且在使用时不应中断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Asthma and COVID-19
Objectives: Highlight the asthma situation in this pandemic. Describe the safety aspects of patients and health professionals. Discuss its severity, control, risk factors, therapeutic management of chronic disease and its exacerbations. Methods: Data were collected from the scientific literature on the topic asthma in the context of the COVID-19 pandemic. A search was performed in PubMed databases, using the descriptors: asthma, coronavirus infections, pandemics, risk factors, drug therapy and spirometry. Results: Asthma has not been identified as a significant risk factor for severe COVID-19 disease, perhaps due to the lower expression of angiotensin-converting enzyme receptors in atopic asthma. Groups were identified, among severe asthmatics, with greater expression of these receptors. Conclusions: Nebulizers should be avoided, spacers should not be shared and spirometry or peak expiratory flow measurement is not recommended. All asthmatics should be maintained on inhaled corticosteroids. Short-acting beta2-agonist only treatment is not recommended from the age of 12. As-needed low dose inhaled corticosteroid with formoterol is the prefered reliever for this age group and can be offered together on the same device. From 6 to 11-years-old, reliever medication should preferably be short-acting beta2-agonists, associated with low dose inhaled corticosteroids and applied in separate devices. In severe asthma, tiotropium should precede the indication of the immunobiological and this, when in use, should not be interrupted.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
10
期刊介绍: Asthma Allergy Immunology has been published three times a year in April, August and December as the official and periodical journal of the Turkish National Society of Allergy and Clinical Immunology since 2003. All articles published in the journal have been available online since 2003. A peer reviewed system is used in evaluation of the manuscripts submitted to Asthma Allergy Immunology. The official language of the journal is English. The aim of the journal is to present advances in the field of allergic diseases and clinical immunology to the readers. In accordance with this goal, manuscripts in the format of original research, review, case report, articles about clinical and practical applications and editorials, short report and letters to the editor about allergic diseases and clinical immunology are published in the journal. The target reader population of the Asthma Allergy Immunology includes specialists and residents of allergy and clinical immunology, pulmonology, internal medicine, pediatrics, dermatology and otolaryngology as well as physicians working in other fields of medicine interested in allergy and immunological diseases.
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