COVID-19感染管理中批准药物再利用的综合综述

IF 1.7 Q3 CHEMISTRY, ORGANIC
Umang Shah, Darshini Patel, Arya Patel, Sandip Patel, Mehul Patel, Ashish D. Patel, Swayamprakash Patel, N. Solanki, Nilesh Pandey
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引用次数: 0

摘要

导致COVID-19大流行的SARS-CoV-2病毒正在席卷全球。因此,由于这种疾病抵抗测试和采用新的治疗方法,重新定位现有药物可能提供一种快速而有吸引力的方法,具有既定的安全性、特性和使用剂量。然而,它们并不具体或集中。然而,人们已经研究了许多药物治疗COVID-19的有效性和安全性,其中大多数药物目前正在进行临床试验。目标是迅速扩大新的预防和治疗药物,以及应用预防方法,如早期患者识别、隔离和治疗。此外,减少通过身体接触传播也很重要。在与这种危险疾病的斗争中,找到适当的治疗方法至关重要。本文综述了几种抗疟疾、抗寄生虫、单克隆抗体、免疫抑制剂和免疫调节剂在COVID-19临床试验中的应用。本文的目的是评估和探索目前在COVID-19中使用的几种药物的潜在作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comprehensive review on repurposing of approved medicine in the management of COVID-19 infection
The SARS-CoV-2 virus, accountable for the COVID-19 pandemic, is now sweeping the globe. As a result, as this disease resists testing and adoption of new treatments, repositioning existing medications may provide a quick and appealing method with established safety, features, and dose used. They are not, however, specific or focused. However, numerous medications have been studied for their efficacy and safety in treatment of COVID-19, with the majority currently undergoing clinical trials. The goal is to rapidly expand novel preventative and therapeutic medications, as well as to apply preventive methods such as early patient identification, isolation, and treatment. Moreover, reducing transmission through physical contact is also important. In the fight against this dangerous disease, finding the proper treatment is crucial. This article summarizes several anti-malarial, anti-parasitic, monoclonal antibodies, immunosuppressant, and immunomodulating agents in clinical trials for COVID-19. The purpose of this article is to evaluate and explore the potential roles of several medications now utilized in COVID-19.
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来源期刊
Organic Communications
Organic Communications CHEMISTRY, ORGANIC-
CiteScore
2.80
自引率
11.80%
发文量
21
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